Evidence map›Paper›PMID 42483591›Full record

ArticleEnvironment & health (Washington, D.C.)2026

Chronic Exposure to Polystyrene Nanoplastics Promotes Lung Cancer Progression via Activating Gluconeogenesis and Inhibiting Glycolysis.

Qian Li, Wenwen Meng, Lang Wen, Chengting Xie, Fei Wang, Ziyi Guo, Zhaoxiang Yan, Yating Deng, Keying Chen, Yuqiao Li and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environment & health (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Qian LiSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Wenwen MengSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Lang WenJoint International Research Laboratory of Reproduction and Development of the Ministry of Education, Chongqing 400016, China.
Chengting XieSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Fei WangSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Ziyi GuoSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Zhaoxiang YanSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Yating DengSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Keying ChenSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Yuqiao LiSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Yixian WenSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.
Tingli HanDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.ORCID https://orcid.org/0000-0001-6011-7508
Fei HanSchool of Public Health, Chongqing Medical University, Chongqing 400016, China.ORCID https://orcid.org/0000-0002-0265-5487

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoplastics (NPs) are emerging as environmental pollutants, yet their long-term impact on lung cancer progression remains largely unexplored. This study explored the influence of extended exposure to polystyrene nanoplastics (PS-NPs) on the growth and movement of A549 lung cancer cells, with particular emphasis on the molecular mechanisms involved in metabolic reprogramming. We demonstrated that prolonged exposure to PS-NPs markedly increased the ability of lung cancer cells to proliferate and migrate. Using an integrated approach combining transcriptomic profiling and C

Indexed as

activating transcription factor-3gluconeogenesisglycolysislung cancernanoplasticsphosphoenolpyruvate carboxykinase 2

Identifiers

PMID42483591
PMCPMC13386385

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.