Evidence map›Paper›PMID 42483485›Full record

ArticleVeterinary medicine international2026

Effects of AD3EC and Ca-P-Mg Supplementation on Oxidative Stress in Postpartum Dairy Cows.

Ameneh Khoshvaghti, Farhad Boti, Saeed Zahmatkesh, Mohaddeseh Shahriyari

Abstract read
In one paragraph

Article in Veterinary medicine international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ameneh KhoshvaghtiDepartment of Clinical Sciences, Kaz.C., Islamic Azad University, Kazerun, Iran, azad.ac.ir.ORCID https://orcid.org/0000-0002-8577-0439
Farhad BotiDepartment of Clinical Sciences, Kaz.C., Islamic Azad University, Kazerun, Iran, azad.ac.ir.ORCID https://orcid.org/0009-0000-5033-8956
Saeed ZahmatkeshDepartment of Clinical Sciences, Kaz.C., Islamic Azad University, Kazerun, Iran, azad.ac.ir.ORCID https://orcid.org/0009-0005-3040-6081
Mohaddeseh ShahriyariDepartment of Clinical Sciences, Kaz.C., Islamic Azad University, Kazerun, Iran, azad.ac.ir.ORCID https://orcid.org/0009-0000-0675-6990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In industrial cattle breeding, special attention is paid to the nutrition of dairy cow livestock production while maintaining animal health. Vitamins and trace minerals such as zinc, copper, and manganese are essential for the functioning of many important proteins in the body. The body's antioxidant system plays a critical role in cell health and, consequently, in the health of body tissues and organs. This defense system helps maintain tissue health by protecting cells against free radicals. Oxidative stress has been found to play a role in the occurrence of many diseases, including metabolic and infectious diseases in organisms. This study measured the effect of vitamin and mineral supplements on serum enzyme antioxidant levels and malondialdehyde concentrations in postpartum dairy cows. In this research, 15 cows received a subcutaneous vitamin supplement (AD3EC) on Day 210 of gestation (single dose) and a single subcutaneous dose of calcium, phosphorus, and magnesium immediately after calving (as a method to enhance the antioxidant immune system of dairy cows due to antioxidant effects of vitamins and minerals, particularly magnesium). These cows were compared to 15 cows that did not receive any vitamin supplements during the dry period but received only calcium in the form of an oral bolus immediately after calving. Serum enzyme antioxidant levels and malondialdehyde were measured using commercial laboratory kits according to standard methods. The results showed the MDA levels decreased but catalase and TAC levels increased in the group that used vitamin and mineral supplements. However, there was no significant change in other parameters. In conclusion, while the consumption of mineral and vitamin supplements does not significantly alter the mean concentrations of superoxide dismutase and glutathione peroxidase, it can reduce oxidative stress by improving the other oxidative stress parameters in dairy Holstein cows.

Indexed as

dairy cowdry periodmineral supplementoxidative stressvitamin supplement

Identifiers

PMID42483485
PMCPMC13386108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.