ArticleJournal of family medicine and primary care2026
Correlation of lipid profile, D-dimer, and insulin resistance among preeclamptic, gestational hypertensive, and healthy normal pregnant women: A comparative cross-sectional study at rural tertiary care centre.
Article in Journal of family medicine and primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Among the various complications, Hypertensive disorder of pregnancy (HDP) has increased maternal and perinatal morbidity and mortality on a global scale. Metabolic changes and abnormalities in Blood coagulation and fibrinolysis are manifestations in patients with HDP, and such changes are related to various metabolic parameters. Aim: To investigate the correlation between lipid profile, D-dimer levels, and insulin resistance in pre-eclampsia, gestational hypertensive, and healthy pregnant women. Materials and Methods: A comparative cross-sectional study conducted in collaboration with the Department of Obstetrics and Gynecology and with Department of Biochemistry at Uttar Pradesh University of Medical Sciences, from January 2022 to July 2023. 120 antenatal women were enrolled in each group (Healthy women as Control, Gestational Hypertension, and Preeclampsia). Pearson's correlation coefficient assessed the relationship between fasting serum insulin and other parameters. Results: Group 1 showed a higher mean serum insulin than Group 2 and controls ( Conclusion: These metabolic biomarkers may play a role in the pathophysiology of these pregnancy-related conditions. Hence, they are implicated in the prognosis of women with HDP.
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