Evidence map›Paper›PMID 42483210›Full record

ArticleRespirology case reports2026

The First Documented Case of Congenital Drug-Resistant Tuberculosis in Indonesia: A Case Report.

Cynthia Centauri, Srisadono Fauzi Adiprabowo, Putri Maharani Tristanita Marsubrin, Irandi Putra Pratomo

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cynthia CentauriDepartment of Pediatrics University of Indonesia - Universitas Indonesia Hospital Depok Indonesia.ORCID https://orcid.org/0009-0007-2034-8046
Srisadono Fauzi AdiprabowoDepartment of Pediatrics University of Indonesia - Universitas Indonesia Hospital Depok Indonesia.
Putri Maharani Tristanita MarsubrinDepartment of Pediatrics University of Indonesia - Universitas Indonesia Hospital Depok Indonesia.ORCID https://orcid.org/0000-0002-5680-6244
Irandi Putra PratomoDepartment of Pulmonology University of Indonesia - Universitas Indonesia Hospital Depok Indonesia.ORCID https://orcid.org/0000-0003-0826-3967

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital drug-resistant tuberculosis (DR-TB) is a rare condition with no standardized treatment. Congenital TB itself is a life-threatening condition. The clinical manifestations can be nonspecific, particularly in preterm infants, which can further reduce diagnostic awareness. We report a case of a 32-week preterm baby with rifampicin-resistant TB. She was born with respiratory distress and early-onset jaundice, initially suspected of sepsis and admitted to the NICU. The infant initially showed clinical improvement at 3 days of life, but at 23 days of life, the clinical condition worsened despite a sterile blood culture. The mother was subsequently diagnosed with miliary TB with rifampicin-resistant Xpert sputum. The infant's gastric lavage Xpert MTB/RIF confirmed rifampicin-resistant TB. At 32 days of life, she received a five-drug regimen, including bedaquiline. She completed 12 months of treatment with a favourable outcome. This case highlights the challenges of early recognition and treatment selection in congenital DR-TB.

Indexed as

congenital tuberculosisdrug‐resistant TBpreterm infanttuberculosisbedaquiline safety

Identifiers

PMID42483210
PMCPMC13385517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.