Evidence map›Paper›PMID 42483149›Full record

Trial reportDepression and anxiety2026

Symptom Trajectories in Patients With Anxiety Disorders During Transdiagnostic Cognitive Behavioral Therapy.

Laura E Meine, Carmen Schaeuffele, Dominique Recher, Miriam Müller-Bardorff, Christina Paersch, Ava Schulz, Isaac Galatzer-Levy, Birgit Kleim

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Depression and anxiety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura E MeineExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0000-0002-2894-9918
Carmen SchaeuffeleDepartment of Education and Psychology, Freie Universität Berlin, Berlin, Germany, fu-berlin.de.ORCID https://orcid.org/0000-0001-5902-0725
Dominique RecherExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0000-0002-9803-7834
Miriam Müller-BardorffExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0000-0002-6231-9960
Christina PaerschExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0000-0002-6319-299X
Ava SchulzExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0000-0003-0923-3524
Isaac Galatzer-LevyDepartment of Psychiatry, New York University Grossman School of Medicine, New York, New York, USA, med.nyu.edu.ORCID https://orcid.org/0000-0003-1864-064X
Birgit KleimExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0000-0001-9114-2917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing research confirms the efficacy of transdiagnostic cognitive behavioral psychotherapy, that is treatments applicable across multiple diagnoses within a disorder class or spectrum, by examining group-level changes from pre- to posttreatment. However, less is known about interindividual differences and dynamic changes during therapy. Understanding different symptom trajectories and their associations with treatment outcome would allow early detection of nonresponders and treatment adjustments. Using data from the treatment group of a randomized controlled trial, we aimed to investigate trajectories in transdiagnostic cognitive behavioral therapy (CBT) with the Unified Protocol (UP) in patients with anxiety disorders. Patients reported on demographics, clinical history, coping strategies, treatment motivation, and expectations before starting transdiagnostic CBT. Participants provided symptom ratings across 16 sessions of the UP as well as at posttreatment, 6-, and 12-month follow-up (

Indexed as

Anxiety DisordersCognitive Behavioral TherapyOutcome Assessment, Health CareAdultFemaleHumansLatent Class AnalysisMaleTreatment Effect HeterogeneityTreatment OutcomeYoung Adultanxiety disorderslatent class growth analysistransdiagnostic cognitive behavioral therapyUnified Protocol

Identifiers

PMID42483149
PMCPMC13387043

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.