ArticleIranian journal of pharmaceutical research : IJPR
Antimalarial Activity of Methoxylated Flavonoid Fraction (Cirsimaritin-Dominated) from
Article in Iranian journal of pharmaceutical research : IJPR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Building on our previous investigation of the total semipolar extract (SPE) of Methods: Aerial parts of Results: Phytochemical analysis of the MFF by HPLC revealed three flavones: 6-methoxytricin (20%), cirsilineol (10%), and cirsimaritin (70%), identified for the first time in Conclusions: This work extends our previous study on the SPE by moving from extract-level observations to constituent-specific insights. By combining phytochemical isolation with in silico receptor interaction analysis, we demonstrate that methoxylated flavonoids, particularly cirsimaritin, are key modulators of host immunity and promising candidates for further development as adjuncts or leads in antimalarial therapy.
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