ArticleCJC open2026
Global Burden of Cardiovascular Diseases in Young Adults Aged 20-24 Years, from 1990-2021: An Analysis of the Global Burden of Disease Study 2021.
Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Temporal trends in acute coronary syndrome among women and association with socioeconomic factors-evidence from a middle-income country.Frontiers in global women's health · 2026Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cardiovascular diseases (CVDs) remain a leading global health threat, with young adults (aged 20-24 years) increasingly affected, despite a historical research focus on older populations. This study investigates global, regional, and national CVD burden trends in this age group from 1990 to 2021 using the Global Burden of Disease Study 2021. Methods: Age-standardized prevalence rate (ASPR), incidence rate (ASIR), death rate (ASDR), and disability-adjusted life years (DALYs) were analyzed for CVDs in those aged 20-24 years. Trends were stratified by sex, region, and sociodemographic index (SDI) levels. Results: Globally, ASIR and ASPR have risen steadily since 1990, accelerating post-2000, whereas the ASDR and DALYs declined after 2006. Female patients exhibited a higher incidence and prevalence, whereas male patients bore greater mortality and DALY burdens. Low and low-middle SDI regions (eg, Oceania, Sub-Saharan Africa, North Africa and the Middle East) faced the highest burdens. Eritrea led in ASIR and ASPR; Nauru had the highest ASDR and DALYs. Ischemic heart disease dominated mortality and DALYs; rheumatic heart disease had the highest prevalence (greater in female patients); and stroke impacted male patients disproportionately. Conclusions: Despite reduced mortality and DALYs, rising CVD incidence and prevalence in young adults-particularly in low-SDI settings-signals a growing public health crisis. Targeted preventive measures, early screening, and health promotion are critical to address this emerging challenge.
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