Evidence map›Paper›PMID 42482932›Full record

ArticleFrontiers in microbiology2026

Domestication reshapes the swine gut microbiome: metagenomic insights into taxonomic and functional divergence across wild and domestic populations.

Zhenhua Yan, Fuchen Zhou, Danyang Lin, Donglin Ruan, Yiyi Liu, Ming Yang, Fanming Meng, Sixiu Huang, Langqing Liu, Enqin Zheng and 3 more

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Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Zhenhua YanState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Fuchen ZhouState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Danyang LinState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Donglin RuanState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Yiyi LiuState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Ming YangCollege of Animal Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong, China.
Fanming MengInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, Guangdong, China.
Sixiu HuangState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Langqing LiuState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Enqin ZhengState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Gengyuan CaiState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Jie YangState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
Zebin ZhangState Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Laboratory for Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, National and Regional Livestock Genebank, Guangdong Gene Bank of Livestock and Poultry, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The gut microbiota constitutes a highly diverse, complex, and dynamically evolving ecosystem within the host. However, the domestication process may alter microbial community composition and function. Here, we investigate these shifts using metagenomic analysis. Methods: Microbial diversity was evaluated using alpha and beta-diversity analysis. Furthermore, LEfSe and Functional analyses were employed to delineate significant disparities in microbial abundance and functional potential between wild boars (WB), Chinese domestic pigs (CDP), and Western domestic pigs (WDP). Results: Our analysis revealed distinct microbial signatures across populations. WB exhibit greater diversity differentiation from WDP, while showing higher similarity to CDP. WB were significantly enriched in the genera Conclusions: These findings indicate that domestication has influenced the swine gut microbiota, contributing to distinct compositional and functional divergences. Future research may explore the potential of reintroducing wild-derived probiotics to enhance domestic pig health.

Indexed as

domesticgut microbiomemetagenomicsmicrobial diversitypig

Identifiers

PMID42482932
PMCPMC13385099

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.