ReviewJournal of clinical and experimental dentistry2026
Comparative evaluation of microneedling technique and diode laser in gingival depigmentation: A prospective randomized study.
Review in Journal of clinical and experimental dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gingival hyperpigmentation due to increased melanocyte activity is a common esthetic concern. Although several depigmentation techniques exist, recurrence remains a clinical challenge. Minimally invasive approaches such as diode laser and microneedling with ascorbic acid have gained attention. Aim: To compare gingival re-pigmentation following depigmentation using diode laser and microneedling with ascorbic acid. Materials and Methods: This randomized controlled study included 32 systemically healthy patients (DOPI 1). Participants were allocated into Group A (diode laser, 940 nm) and Group B (microneedling with topical ascorbic acid). Clinical parameters-Visible Plaque Index (VPI), Modified Gingival Index (MGI), and Dummett-Gupta Oral Pigmentation Index (DOPI)-were recorded at baseline, 3, 6, and 12 months. Pain was assessed using VAS. Results: Both groups showed significant reductions in DOPI from baseline to 12 months (p = 0.0001). Near-complete depigmentation was observed at 3 months, with mild re-pigmentation at 12 months (0.42 ± 0.34 and 0.47 ± 0.22), without significant intergroup differences (p > 0.05). Microneedling showed higher 24-hour VAS scores, but pain resolved in both groups by day 7. VPI and MGI improved significantly in both groups (p = 0.0001). Conclusions: Both modalities are effective, safe, and cost-effective, with comparable long-term outcomes. Diode laser demonstrated lower immediate postoperative discomfort.
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Registered trials
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