Combination Approach to Hyperpigmentation: Unveiling Enhanced Aesthetic Results With Microneedling and Pigment-Correcting Peel.

Suneel Chilukuri, Isabel Diaz, Bianca Gonzalez, Lia Arvanitidou

Abstract read

In one paragraph

Article in The Journal of clinical and aesthetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suneel ChilukuriDr. Chilukuri is with Refresh Dermatology, Houston, Texas.

Isabel DiazMs. Diaz, Ms. Gonzalez, and Dr. Arvanitidou are with Colgate-Palmolive Company, Piscataway, New Jersey.

Bianca GonzalezMs. Diaz, Ms. Gonzalez, and Dr. Arvanitidou are with Colgate-Palmolive Company, Piscataway, New Jersey.

Lia ArvanitidouMs. Diaz, Ms. Gonzalez, and Dr. Arvanitidou are with Colgate-Palmolive Company, Piscataway, New Jersey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo demonstrate the safety and enhanced cosmetic outcomes of the combination of microneedling with a pigment-correcting peel when treating hyperpigmented skin across diverse Fitzpatrick skin types.

methodsA total of 31 patients (Fitzpatrick skin types I-V) with facial hyperpigmentation were enrolled in the study. Each participant received 2 different treatments on the face: 1 side was treated with a pigment-correcting peel combined with microneedling, while the other side received microneedling alone (3 sessions, 4 weeks apart). Assessments included Mexameter measurements, dermatologist grading, and standardized clinical imaging. Self-assessment questionnaires were completed by participants at different timepoints.

resultsThe 31 participants completed the study; both microneedling alone and the combination treatment were well tolerated. The combined approach yielded significantly better results according to dermatologist efficacy assessment for clarity/brightness, evenness of skin tone (pigmentation and redness), overall appearance and texture ( LIMITATIONS: A primary limitation of this study was the restricted assessment window, which proved to be insufficient to achieve significant clinical improvement for parameters such as fine lines, wrinkles, and pore size.

conclusionThis research showed that combining a pigment-correcting peel with microneedling can be significantly more effective at improving overall skin appearance than microneedling alone. This combined therapy was safe, well tolerated, and preferred by participants across a diverse population.

Indexed as

Chemical peelhyperpigmentationmicroneedlingpeelphotoagingskin rejuvenation

Identifiers

PMID42482855

PMCPMC13387663

What OpenQuestion holds

Textmetadata

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.