ArticleTransplantation direct2026
Simultaneous Pancreas and Kidney Transplant Recipients From Pediatric Donors Have Comparable Outcomes to Those From Adult Donors, Regardless of the Type of Donation.
Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
11 authors.
Funding
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Abstract
Background: Increased use of pediatric donors or donation after circulatory death (DCD) donors could enlarge the pancreas transplant donor pool. Pediatric donors and DCD donors are underutilized but are associated with similar outcomes following simultaneous pancreas and kidney (SPK) transplantation, compared with adult donation after brain death (DBD) donors. However, SPK outcomes from donors in whom both variables are present are unknown. Methods: Recipients were categorized into 4 groups based on the age of the donor and types of donations: DBD/≥18 y, DBD/<18 y, DCD/≥18 y, and DCD/<18 y. Kidney and pancreas graft functions were compared at various time frames. Risk of graft failure was the primary outcome. Results: Of 234 SPK recipients, 127 (54%) were DBD/≥18 y, 43 (18%) DBD/<18 y, 49 (21%) DCD/≥18 y, and 15 (6%) DCD/<18 y. There were no significant differences among the groups in overall or death-censored graft failure of either organ. Multivariable analysis (reference to DBD/≥18) showed no significant risk for pancreas uncensored graft failure for DBD/<18 y (hazard ratio [HR], 0.58; 95% confidence interval [CI], 0.23-1.44; Conclusions: SPK transplants using DCD organs from pediatric donors can be used without compromising outcomes.
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