ArticleHealth science reports2026
Prevalence and Case Fatality of Congenital Heart Disease in Pakistani Infants: A 11-Year Retrospective Time-Series Analysis.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Prevalence and Case Fatality of Congenital Heart Disease in Pakistani Infants: A 11-Year Retrospective Time-Series Analysis.Health science reports · 2026Article
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Authors and funding
9 authors.
Funding
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Abstract
Background and Aims: Congenital heart disease (CHD) is a significant cause of infant mortality. In Pakistan, inadequate screening in healthcare settings and under-reporting of CHD cases contribute to high mortality and morbidity rates. This study aimed to determine the prevalence and case fatality rate of CHD over a decade among neonates and post-neonatal infants in Buner, Khyber Pakhtunkhwa (KP), Pakistan. Clarifying the epidemiological profile of CHD in this region is vital for strengthening early detection in newborns. Methods: This retrospective, single-center study was conducted at the District Headquarter Hospital, District Buner. Data related to various parameters were extracted from hospital records and presented as prevalence and case fatality rate (CFR). Time-series analysis was performed to assess trends over the years. Results: During the study period, a total of 733 cases of CHD were identified among 78,713 newborns. Of these cases, 415 (56.6%) were male infants, while 318 (43.4%) were female. The prevalence rate varied, with a peak in 2023 at 17.05 per 1000 and a trough in 2018 at 5.15 per 1000. Over the 11 years, the overall CFR was 36.7%, with the highest in 2021 at 68.1% and the lowest in both 2015 and 2018 at 27.7% each. The number of CHD cases increased significantly over time, rising from 47 (0.86%) in 2013 to 139 (1.7%) in 2023. Conclusion: The data indicate a consistent rise in CHD cases, along with an increasing case fatality rate and prevalence over the years in District Buner, Pakistan. This study underscores the need for improved screening protocols for CHD and the adoption of electronic health records to enable timely reporting of CHD cases among neonates and post-neonatal infants.
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