ReviewBMJ oncology2026
Identification and management of genetic susceptibility to cancer: UK perspective.
Review in BMJ oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is a genomic disease caused by variants in genes that impact on the regulation of cell division, cell growth and cell death. While the majority of cancers are caused by acquired genomic variation, a significant minority are influenced by inherited genetic variation which can increase the chance of a person developing cancer in their lifetime. Inherited genetic factors can be monogenic or polygenic and also interact with other cancer risk factors to create an individualised risk profile. Understanding personalised cancer risk can facilitate precision screening, prevention and early detection strategies. In this review, we give an overview of constitutional genetic susceptibility to cancer, how to assess and identify enhanced susceptibility and exemplars of how this influences precision management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.