Evidence map›Paper›PMID 42482447›Full record

ArticleVirulence2026

Natural molecule potentiates colistin efficacy

Hui-Hui Zhang, Yi-Dan Cao, Ying-Ying Xie, Yu-Ze Li, Xiao-Na Fan, Qiu-Yue Diao, Yu-Jiao Liang, Li-Ren He, Zi-Xing Zhong, Li-Juan Xia and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hui-Hui ZhangState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-2335-7884
Yi-Dan CaoState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Ying-Ying XieState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yu-Ze LiState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xiao-Na FanState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Qiu-Yue DiaoState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yu-Jiao LiangState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Li-Ren HeState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zi-Xing ZhongState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Li-Juan XiaState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Ze-Hua CuiState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xiao-Ping LiaoState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-4654-5837
Xin-Lei LianState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Dong-Hao ZhaoState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Jian SunState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-4209-7555
Hao RenState Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0003-4182-8886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colistin holds clinical importance as a last resort therapy against infections caused by multidrug-resistant Gram-negative pathogens. In addition to well-studied plasmid-encoded

Indexed as

Anti-Bacterial AgentsColistinFerroptosisFlavanonesLipopolysaccharidesAnimalsBacterial ProteinsCell MembraneDrug SynergismEscherichia coliIronMiceMicrobial Sensitivity TestsTranscription FactorsAnti-Bacterial AgentsBacterial ProteinsbaicaleinColistinFlavanonesIronLipopolysaccharidespmrA protein, BacteriaTranscription FactorsAntibiotic resistancecolistinferroptotic-like damageLPS modificationstwo-component system

Identifiers

PMID42482447
PMCPMC13418482

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.