Evidence map›Paper›PMID 42482433›Full record

ArticleAdvanced healthcare materials2026

Portable Molecularly Imprinted Polymer Sensor for Rapid Swab-Based Detection of Norovirus.

Amy Dann, Pankaj Singla, Minji Kim, Sloane Stoufer, Clare Thomas, Robert D Crapnell, Craig E Banks, Jake McClements, Shayan Seyedin, Mark Geoghegan and 4 more

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Amy DannDepartment of Chemical Engineering, Nancy Rothwell Building, University of Manchester, Manchester, UK.
Pankaj SinglaDepartment of Chemical Engineering, Nancy Rothwell Building, University of Manchester, Manchester, UK.
Minji KimDepartment of Food Science, University of Massachusetts, Amherst, Massachusetts, USA.
Sloane StouferDepartment of Food Science, University of Massachusetts, Amherst, Massachusetts, USA.
Clare ThomasSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, UK.
Robert D CrapnellFaculty of Science and Engineering, Dalton Building, Manchester Metropolitan University, Manchester, Great Britain.
Craig E BanksFaculty of Science and Engineering, Dalton Building, Manchester Metropolitan University, Manchester, Great Britain.ORCID https://orcid.org/0000-0002-0756-9764
Jake McClementsSchool of Engineering, Merz Court, Newcastle University, Newcastle Upon Tyne, UK.ORCID https://orcid.org/0000-0003-2748-9945
Shayan SeyedinSchool of Engineering, Merz Court, Newcastle University, Newcastle Upon Tyne, UK.
Mark GeogheganSchool of Engineering, Merz Court, Newcastle University, Newcastle Upon Tyne, UK.ORCID https://orcid.org/0000-0001-9919-7357
Samuel T JonesSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, UK.ORCID https://orcid.org/0000-0002-3907-0810
Christopher F BlanfordManchester Institute of Biotechnology, The University of Manchester, Manchester, UK.
Matthew D MooreDepartment of Food Science, University of Massachusetts, Amherst, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5393-0733
Marloes PeetersDepartment of Chemical Engineering, Nancy Rothwell Building, University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0002-0429-8073

Funding

National Institute of Food and Agriculture
6 · The paper itself

Abstract

Norovirus poses a continuous challenge for healthcare systems, leading to increased hospital admissions, infection-control demands, and costly outbreak management. Gold-standard diagnostics such as real-time reverse transcriptase polymerase chain reaction (RT-PCR) require specialized laboratory equipment and trained personnel. This work reports a portable electrochemical sensor based on an electropolymerized molecularly imprinted polymer fabricated directly on an electrode surface for rapid norovirus detection using voltametric read-out. The sensor was tested against four norovirus virus-like particle (VLP) genotypes that each exhibited consistent responses across a broad concentration range. Sensor specificity and selectivity were demonstrated through comparison with a nontarget imprinted control polymer and testing against four nontarget live viruses. The imprinted polymer electrodes showed excellent stability, with no significant loss of performance after storage under ambient conditions for up to three months. For practical applicability, nitrile gloves were inoculated with each VLP genotype and sampled using standard swabbing procedures. The entire process was completed in ∼ 15 min, with electrochemical acquisition completed in 20 s. Successful detection of each genotype was achieved with detection limits between 154 and 279 fg/mL (8.78 × 10

Indexed as

Biosensing TechniquesMolecular ImprintingMolecularly Imprinted PolymersNorovirusPolymersCaliciviridae InfectionsElectrochemical TechniquesHumansRapid Diagnostic TestsMolecularly Imprinted PolymersPolymersbiomimetic sensorelectrochemical detectionfood safetymolecularly imprinted polymernoroviruspublic health

Identifiers

PMID42482433
PMCPMC13495804

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.