Evidence map›Paper›PMID 42482241›Full record

ArticleJournal of medical case reports2026

Transnasal endoscopy and the use of virtual reality: a case report.

Vrinda Bhardwaj, Chelsea C Okoro, Saloni Dangoria, Jeffrey I Gold

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vrinda BhardwajKeck School of Medicine, Department of Pediatrics, University of Southern California, Los Angeles, USA. vbhardwaj@chla.usc.edu.
Chelsea C OkoroDepartment of Anesthesiology Critical Care Medicine, The Biobehavioral Pain Lab, The Saban Research Institute at Children's Hospital Los Angeles, Los Angeles, USA.
Saloni DangoriaDepartment of Anesthesiology Critical Care Medicine, The Biobehavioral Pain Lab, The Saban Research Institute at Children's Hospital Los Angeles, Los Angeles, USA.
Jeffrey I GoldDepartment of Anesthesiology Critical Care Medicine, The Biobehavioral Pain Lab, The Saban Research Institute at Children's Hospital Los Angeles, Los Angeles, USA.ORCID http://orcid.org/0000-0003-4493-1299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren diagnosed with eosinophilic esophagitis (EoE) often require repeated esophagogastroduodenoscopy (EGD) procedures to monitor disease progression and treatment response. These procedures typically involve general anesthesia, which is associated with short-term side effects and potential long-term risks. Transnasal endoscopy (TNE) has emerged as a less invasive alternative to EGD that can be performed without anesthesia. The use of virtual reality (VR) during TNE eliminates anesthesia exposure in patients requiring repeated EGD, while enhancing patient comfort and procedural success. CASE PRESENTATIONS: The objective of this case study is to detail the experience of a 12-year-old, Caucasian, male patient diagnosed with EoE. The patient previously underwent multiple EGD procedures to monitor disease progression, resulting in repeated anesthesia exposures. In hopes of reducing anesthesia exposure, the patient and their family opted to explore sedation-sparing alternatives to EGD, marking the patients first TNE. Despite high baseline anxiety, the patient tolerated their initial TNE procedure without vomiting or gagging, required less than one hour in the clinic per visit, experienced no post-procedural recovery time, and requested VR for follow-up TNE procedures. Utilizing VR enabled a successful, sedation-free TNE in a highly anxious pediatric patient, supporting VR as an effective sedation-sparing substitute for painful procedures.

conclusionsThis case highlights the potential of VR as a non-pharmacologic tool to enhance the tolerability of TNE in pediatric patients, thereby minimizing sedation-associated health risks in children requiring frequent endoscopic monitoring.

Indexed as

Eosinophilic EsophagitisVirtual RealityChildEndoscopy, Digestive SystemHumansMaleTreatment OutcomeCase reportDigital therapeuticsGastroenterologyPediatricsTransnasal endoscopyVirtual reality

Identifiers

PMID42482241
PMCPMC13393687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.