ArticleBMC pregnancy and childbirth2026
Maternal age and perinatal morbidity: a comparative cohort study including advanced maternal age and adolescent pregnancy.
Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaternal age at childbirth shows a bimodal risk distribution worldwide. While adolescent pregnancy remains common in many areas, the rate of advanced maternal age is rising in high-income countries. Both extremes are associated with adverse outcomes through different pathways. This study tests the hypothesis that adolescent (< 19 years) and older (> 35 years) mothers face higher obstetric and neonatal risks than young adults (19-35 years), regardless of key confounders.
methodsA retrospective cohort study was conducted from 2019 to 2023 at a tertiary-care center. A total of 19,728 mother-neonate dyads were included and stratified by maternal age: adolescents (n = 1,570), young adults (n = 14,707), and older adults (n = 3,451). We analyzed maternal demographics, antenatal care, and maternal-neonatal outcomes. Multivariable logistic regression was adjusted for confounders, including socioeconomic status, parity, prenatal care, and comorbidities. Primary outcomes included mode of delivery, preterm birth, low birth weight, preeclampsia, and neonatal intensive care unit (NICU) admission.
resultsOlder adult mothers showed the highest adjusted risks: preeclampsia (aOR = 3.15, 95% CI: 2.82-3.52), cesarean delivery (aOR = 1.89, 1.72-2.08), and preterm birth (aOR = 2.94, 2.68-3.22). Adolescent mothers had lower cesarean rates but significantly higher adjusted odds of low birth weight (aOR = 1.72, 1.45-2.04) and preterm birth (aOR = 1.48, 1.25-1.75). The likelihood of NICU admission increased for both groups. Socioeconomic disadvantage was most apparent among adolescents, while medical comorbidities characterized the older group.
conclusionThis study confirms a U-shaped risk curve, with both adolescent and advanced maternal ages remaining associated with increased risk after adjustment for measured confounders for adverse pregnancy outcomes. The findings highlight the need for specific, age-tailored clinical and public health strategies: targeted social support and early prenatal care for adolescents, and careful monitoring and management of medical comorbidities for older mothers.
Indexed as
Identifiers
42482181What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.