Evidence map›Paper›PMID 42482140›Full record

ArticleBMC pharmacology & toxicology2026

Elucidating metabolic dysfunction induced by titanium dioxide in intestinal epithelial cells using an integrative approach of metabolomics and transcriptomics.

Xinchen Wang, Shilong Jiang, Zhengyu Gu

Abstract read
In one paragraph

Article in BMC pharmacology & toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinchen WangSchool of Basic Medical Sciences, Kangda College of Nanjing Medical University, Lianyungang, 222000, China.
Shilong JiangHeilongjiang Feihe Dairy Co., Ltd., Beijing, 100015, China. jiangshilong@feihe.com.
Zhengyu GuDepartment of Gastroenterology, Nanjing Redcross Hospital, Nanjing, 210001, China. guzhengyu1979@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTitanium dioxide (TiO

methodsIn this study, we investigated the impact of TiO

resultsTranscriptomic analysis identified differentially expressed genes associated with disruptions in cellular components, molecular functions, and biological processes, collectively pointing to mechanisms underlying TiO

conclusionsIn conclusion, our findings elucidate the metabolic mechanisms driving TiO

Indexed as

Epithelial CellsIntestinal MucosaTitaniumAnimalsCaco-2 CellsGene Expression ProfilingHumansMetabolomicsMultiomicsTranscriptomeTitaniumtitanium dioxideFood toxicologyIntestinalTitanium dioxideToxicology

Identifiers

PMID42482140
PMCPMC13679024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.