Evidence map›Paper›PMID 42482055›Full record

ArticleRadiation oncology (London, England)2026

Stereotactic radiosurgery using a self-shielded gyroscopic radiosurgery system for meningiomas: technical aspects and dosimetric results.

Yongsook C Lee, Rupesh Kotecha, Robert H Press, Noah S Kalman, Matthew D Hall, D Jay Wieczorek, Ranjini Tolakanahalli, Minesh P Mehta, Michael W McDermott, Alonso N Gutierrez

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yongsook C LeeDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA. dr.cecilialee@hotmail.com.
Rupesh KotechaDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Robert H PressDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Noah S KalmanDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Matthew D HallDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
D Jay WieczorekDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Ranjini TolakanahalliDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Minesh P MehtaDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Michael W McDermottDepartment of Translational Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.
Alonso N GutierrezDepartment of Radiation Oncology, Herbert Wertheim Cancer Institute, Baptist Health South Florida, Miami, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ZAP-X

methodsUnique technical aspects of our treatment workflow using the ZAP-X system encompassing computed tomography simulation, treatment planning, independent dose calculations, patient-specific quality assurance (PSQA) and treatment delivery were described. Eighteen single-lesion meningioma patients, who were treated following this workflow, were selected and divided into two groups (Group A [thirteen patients]: 25 Gy in five fractions, FSRS); Group B [five patients]: 15 Gy in a single fraction, SRS). Plan quality metrics, independent dose calculations and PSQA for each group were reviewed and analyzed.

resultsFor Group A, mean age (range) was 60 years (35 years - 80 years) and mean planning target volume (PTV) (range) was 4.78 cc (2.10 cc - 9.38 cc). Mean (range) PTV coverage, prescribed isodose line, Paddick conformity index, gradient index, number of isocenters, number of beams, delivery time estimate per fraction and PSQA gamma passing rate were 99.5% (99.5% - 99.6%), 53.5% (50.1% - 61.3%), 0.89 (0.83-0.93), 2.64 (2.54-2.88), 11.8 (5-19), 208.5 (91-332), 43.6 min (24.5 -61.0 min) and 95.0% (91.5% - 98.4%), respectively. For Group B, corresponding values were 70 years (62 years - 75 years), 1.12 cc (0.77 cc - 1.99 cc), 99.5% (99.5% - 99.5%), 56.4% (50.6% - 62.8%), 0.89 (0.85-0.93), 2.95 (2.63-3.22), 7.2 (5-9), 102.4 (81-132), 33.9 min (27.3 -38.9 min) and 95.3% (91.1% - 100.0%). For all beams in both groups, independent dose calculations were < ± 0.02% of treatment planning system dose calculations.

conclusionsOur experience with SRS and FSRS using the ZAP-X system for meningioma patients demonstrated that a typical external beam radiotherapy workflow was applicable with unique technical aspects, and treatment plans met our institutional planning goals and were concordant with independent dose calculations and PSQA.

Indexed as

Meningeal NeoplasmsMeningiomaRadiosurgeryRadiotherapy Planning, Computer-AssistedAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRadiotherapy DosageGyroscopicMeningiomasSelf-shieldedStereotactic radiosurgeryZAP-X

Identifiers

PMID42482055
PMCPMC13474973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.