Evidence map›Paper›PMID 42481883›Full record

ArticleSpine deformity2026

Toward biomechanically optimized intraoperative correction in lumbar vertebral body tethering.

Marine Gay, A Noelle Larson, Melanie Boeyer, Nikita Cobetto, Christiane Caouette, Isabelle Villemure, Dan Hoernschemeyer, Ahmet Alanay, Ron El-Hawary, Carl-Eric Aubin

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Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Marine GayDepartment of Mechanical Engineering, Polytechnique Montréal, Downtown Station, P.O. Box 6079, Montreal, QC, H3C 3A7, Canada.
A Noelle LarsonDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Melanie BoeyerDepartment of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA.
Nikita CobettoDepartment of Mechanical Engineering, Polytechnique Montréal, Downtown Station, P.O. Box 6079, Montreal, QC, H3C 3A7, Canada.
Christiane CaouetteDepartment of Mechanical Engineering, Polytechnique Montréal, Downtown Station, P.O. Box 6079, Montreal, QC, H3C 3A7, Canada.
Isabelle VillemureDepartment of Mechanical Engineering, Polytechnique Montréal, Downtown Station, P.O. Box 6079, Montreal, QC, H3C 3A7, Canada.
Dan HoernschemeyerDepartment of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA.
Ahmet AlanayDepartment of Orthopedics and Traumatology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey.
Ron El-HawaryBoston Children's Hospital, Boston, MA, USA.
Carl-Eric AubinDepartment of Mechanical Engineering, Polytechnique Montréal, Downtown Station, P.O. Box 6079, Montreal, QC, H3C 3A7, Canada. carl-eric.aubin@polymtl.ca.ORCID http://orcid.org/0000-0003-2374-008X

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2023-04372Scoliosis Research Society 980785
6 · The paper itself

Abstract

purposeTo identify the appropriate intraoperative correction in lumbar vertebral body tethering (VBT) to optimize outcomes and to avoid under- or over-correction at skeletal maturity by accounting for preoperative deformity size and stiffness, body weight, and skeletal maturity.

methodsFifteen cases of pediatric idiopathic scoliosis (average lumbar Cobb angle: 48° (40-59°) were used to build validated 3D patient-specific finite element models, which were calibrated to various preoperative characteristics. Physics-based numerical simulations of VBT were performed in the intraoperative lateral decubitus position, with actual instrumented vertebrae (T10-T12 to L2-L4). Intraoperative correction levels (from 50 to 90%) were simulated under four growth remaining scenarios corresponding to Sanders Stage (SS) 3A, 3B, 4, and 5. Postoperative growth and growth modulation were simulated over a 2-year period. The targeted result was a curve at 10° ± 5° at 2-year follow-up.

resultsSimulations indicated that achieving the targeted two-year coronal correction required significantly lower intraoperative correction in SS 3A compared with the more mature stages (3B, 4, 5) (p < 0.01). No significant differences were observed among SS 3B, 4, and 5. The corresponding target intraoperative corrections were 65% (53-75%), 72% (60-80%), 73% (60-80%), and 73% (68-80%) for SS 3A, 3B, 4, and 5, respectively. Separately, body weight and spinal flexibility did not statistically impact the intraoperative target. However, their interaction significantly influenced the intraoperative correction targets in SS 3A and 3B cases (p < 0.05).

conclusionOptimal intraoperative correction in lumbar VBT appears to depend primarily on preoperative skeletal maturity status. In patients who are more immature, body weight and spinal flexibility should also be considered when selecting correction targets. This simulating tool could be used as a planning tool to provides a pathway toward precise, individualized intraoperative correction strategies aimed at improving the reliability of VBT outcomes.

Indexed as

Finite-element modelingGrowth modulation correctionOvercorrectionPediatric idiopathic scoliosisVertebral body tethering

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.