Evidence map›Paper›PMID 42481822›Full record

ArticleEating and weight disorders : EWD2026

Interoception and borderline personality disorder in female adolescents with restrictive eating disorders.

Anna Riva, Carlo Panarella, Gabriele Arienti, Simona Di Guardo, Eleonora Brasola, Renata Nacinovich, Andrea E Cavanna

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Article in Eating and weight disorders : EWD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Anna RivaDepartment of Child Neuropsychiatry, Fondazione IRCCS San Gerardo Dei Tintori, 20900, Monza, Italy.
Carlo PanarellaDepartment of Child Neuropsychiatry, Fondazione IRCCS San Gerardo Dei Tintori, 20900, Monza, Italy.
Gabriele ArientiDepartment of Child Neuropsychiatry, Fondazione IRCCS San Gerardo Dei Tintori, 20900, Monza, Italy.
Simona Di GuardoDepartment of Child Neuropsychiatry, Fondazione IRCCS San Gerardo Dei Tintori, 20900, Monza, Italy.
Eleonora BrasolaDepartment of Child Neuropsychiatry, Fondazione IRCCS San Gerardo Dei Tintori, 20900, Monza, Italy.
Renata Nacinovich *School of Medicine and Surgery, Università degli Studi di Milano - Bicocca, Via Cadore 48, 20900, Monza, Italy. renata.nacinovich@unimib.it.
Andrea E Cavanna *School of Medicine and Surgery, Università degli Studi di Milano - Bicocca, Via Cadore 48, 20900, Monza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInteroception has been reported to be impaired in patients with restrictive eating disorders (REDs), while its role in patients with borderline personality disorder (BPD) is more controversial. We set out to conduct a clinical study to explore the relationship between interoception, eating disorders, and BPD.

methodsWe recruited a sample of 75 female adolescents affected by REDs, of whom 21 received a diagnosis of comorbid BPD. In addition to collecting demographic and clinical data, we administered measures of interoceptive awareness (MAIA-2), the scale for eating symptomatology (EDI-3), and alexithymia (TAS-20) to all patients.

resultsPatients with REDs and comorbid BPD reported lower scores on the MAIA-2 Not-Distracting (p = 0.046) and Trusting (p = 0.023) subscales, reflecting decreased focus and reliance on bodily sensations of pain or discomfort compared to patients with REDs only. Lower scores on the MAIA-2 Trusting subscale were associated with higher scores on all EDI-3 subscales and on the total TAS-20 scale (p = 0.005), whereas lower scores on the MAIA-2 Not-Worrying subscale were associated with higher scores on the EDI-3 Interpersonal Problems composite subscale (p = 0.049), and higher scores on the MAIA-2 Noticing subscale were associated with higher scores on the EDI-3 Affective Problems composite subscale (p = 0.003).

conclusionsInteroceptive dysfunction appears to be a key vulnerability factor for eating disorder psychopathology in female adolescents with REDs, with comorbid BPD potentially further exacerbating these impairments. Targeting interoceptive processes may represent a promising therapeutic approach to improve emotion regulation and clinical outcomes, particularly in patients with co-occurring BPD, and warrants further investigation in this clinical population. Level III Evidence obtained from cohort or case-control analytic studies.

Indexed as

Borderline Personality DisorderFeeding and Eating DisordersInteroceptionAdolescentAwarenessComorbidityFemaleHumansAdolescentsBorderline personality disorderInteroceptionRestrictive eating disorders

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.