ArticleNature microbiology2026
Molecular and cellular insights into the parasitic infection of bloom-forming marine diatoms by Pirsonia diadema.
Article in Nature microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Molecular and cellular insights into the parasitic infection of bloom-forming marine diatoms by Pirsonia diadema.Nature microbiology · 2026Article
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12 authors.
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Abstract
Microbial host-parasite interactions shape global biogeochemical cycles, yet their cellular and evolutionary mechanisms remain poorly understood. Here we developed a model pathosystem to explore the interaction between the eukaryotic microparasite, Pirsonia diadema, and its host, the bloom-forming diatom, Coscinodiscus. Culture conditions recapitulated Pirsonia's rapid life cycle in vitro, and live-cell imaging enabled the quantitative analysis of infection dynamics and host mortality. Genome sequencing and time-resolved dual RNA sequencing of Pirsonia revealed unique genetic innovations relative to their oomycete relatives and an upregulation of an expanded multi-gene family of integrin-like proteins in Pirsonia zoospores during infection. Targeted drug perturbations combined with ultrastructure expansion microscopy confirm stage specific roles for Pirsonia's cytoskeleton, including actin-dependent host attachment and formation of intracellular parasite-induced feeding structures and microtubule-associated processes in zoospore differentiation. Together, these findings reveal mechanisms underpinning Pirsonia infection and provide insights into the evolution of strategies that underpin parasitic shunts in marine trophic networks.
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