Evidence map›Paper›PMID 42481513›Full record

ArticleNature communications2026

Catalytic electrophilic arene C-H chlorination by rethinking the century-old Willgerodt reagent.

Qi-Qi Hu, Yao Xiang, Zhaobo Ying, Yu Zhou, Hui Zhou, Youwei Xie

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qi-Qi HuHubei Key Laboratory of Bioinorganic Chemistry and Materia Medica; School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, China.ORCID http://orcid.org/0000-0002-1691-7978
Yao XiangHubei Key Laboratory of Bioinorganic Chemistry and Materia Medica; School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, China.
Zhaobo YingHubei Key Laboratory of Bioinorganic Chemistry and Materia Medica; School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, China.
Yu ZhouCollege of Chemistry, Central China Normal University (CCNU), 152 Luoyu Road, Wuhan, China. zhouyu@cuhk.edu.cn.
Hui ZhouCollege of Chemistry, Central China Normal University (CCNU), 152 Luoyu Road, Wuhan, China. huizhou@ccnu.edu.cn.ORCID http://orcid.org/0000-0001-7474-203X
Youwei XieHubei Key Laboratory of Bioinorganic Chemistry and Materia Medica; School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, China. xieyw@hust.edu.cn.ORCID http://orcid.org/0000-0003-3831-4059

Funding

National Science Foundation of China | National Natural Science Foundation of China-Yunnan Joint Fund (NSFC-Yunnan Joint Fund) 22171095National Science Foundation of China | National Natural Science Foundation of China-Yunnan Joint Fund (NSFC-Yunnan Joint Fund) 22401102
6 · The paper itself

Abstract

An elusive variant of the Willgerodt reagent (III) with anticipated high electrophilicity has been successfully synthesized and unambiguously characterized by both nuclear magnetic resonance (NMR) and single-crystal X-ray crystallography. Compared to previous I-Cl type λ

Identifiers

PMID42481513
PMCPMC13507120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.