Evidence map›Paper›PMID 42481511›Full record

ArticleNature communications2026

Mechanistic studies of the human NIPA2 transporter.

Sebastian J Karuppan, Nikolas Connolly, Simran Shrestha, Matthew Medearis, Maryam Gholampour, Lejla Zubcevic

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sebastian J KaruppanDepartment of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, USA.
Nikolas Connolly *Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, USA.
Simran Shrestha *Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, USA.ORCID http://orcid.org/0009-0006-8521-5546
Matthew MedearisDepartment of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, USA.
Maryam GholampourDepartment of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, USA.
Lejla ZubcevicDepartment of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS, USA. lzubcevic@kumc.edu.ORCID http://orcid.org/0000-0002-1884-9235

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
Cryo-EM for the Midwest RegionS10OD036339 · OD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI FREUDENTHAL, BRET D · 2024 to 2024
$2.0M
Esther A. and Joseph Klingenstein Fund (Esther A. & Joseph Klingenstein Fund, Inc.) n/aNIGMS NIH HHS U24 GM129547NIH HHS S10 OD036339
6 · The paper itself

Abstract

The Non-Imprinted in Prader-Willi/Angelman syndrome 2 (NIPA2) is a highly conserved member of the Drug/Metabolite Transporter (DMT) family, originally characterized as a Mg

Indexed as

Membrane ProteinsAnimalsBiological TransportCryoelectron MicroscopyHEK293 CellsHumansLiposomesMagnesiumMutationNucleotidesLiposomesMagnesiumMembrane ProteinsNucleotides

Identifiers

PMID42481511
PMCPMC13500462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.