Evidence map›Paper›PMID 42481190›Full record

ArticleBMJ open2026

Understanding the implementation of kidney supportive care interventions to improve palliative care outcomes for adults receiving haemodialysis: protocol for a rapid realist review.

Chalani Lasanthika, Barnaby Hole, Ala Szczepura, Ann Bonner, Jane Coad, Emma Murphy

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chalani LasanthikaCentre for Healthcare & Community Transformation, Coventry University, Coventry, UK thalaowitc@uni.coventry.ac.uk.ORCID http://orcid.org/0000-0001-7891-8864
Barnaby HolePalliative and End of Life Care Research Group & Population Health Sciences Research Group, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0003-2414-1302
Ala SzczepuraCentre for Healthcare & Community Transformation, Coventry University, Coventry, UK.ORCID http://orcid.org/0000-0001-6244-9872
Ann BonnerSchool of Nursing and Midwifery, Griffith University, Southport, Queensland, Australia.ORCID http://orcid.org/0000-0001-9920-6743
Jane CoadCentre for Care Excellence, Coventry University and University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Emma MurphyCentre for Care Excellence, Coventry University and University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) is a significant global health concern, contributing substantially to mortality; in advanced stages, adults often require kidney supportive care (KSC), a model of care/intervention that addresses complex palliative and supportive needs. These needs often remain insufficiently addressed, particularly among adults receiving haemodialysis, due to the interplay of multiple contextual factors and inconsistent reported outcomes. Consequently, it remains unclear how, for whom and under what circumstances KSC works (or does not work). Therefore, this rapid realist review aims to identify the key contexts in which KSC interventions have been implemented and the mechanisms that influenced palliative care outcomes for adults receiving haemodialysis. METHODS AND ANALYSIS: Rapid realist review is a structured, theory-driven approach to evidence synthesis conducted within a condensed timeframe, aiming to explain how and why interventions work, for whom and in what contexts, to identify effective models of service delivery. This rapid realist review will be conducted following a multiple-step process, including defining the project scope and research questions development (including how the findings will be utilised); development of search terms and identification of relevant literature; quality appraisal; data extraction and preliminary programme theory development; validation and refinement of programme theory with content experts; and dissemination of findings.A systematic literature search will be conducted from 2020 to 2025 using the following databases: MEDLINE, CINAHL, PsycINFO, Cochrane Central Register of Controlled Trials, Scopus and Academic Search Complete, with supplementary forward and backward citation tracking. Two reviewers will screen titles and abstracts for relevant research, and the full papers selected will be used to extract data and assess the quality of evidence based on relevance, richness and rigour. Data extraction and synthesis will be conducted iteratively to identify context-mechanism-outcome configurations (CMOCs), which will inform the development and refinement of the programme theory, rather than simply informing palliative care outcomes.A 10-member expert panel will review, evaluate and reflect on the initial CMOCs in light of their clinical expertise and personal experience. The reporting of findings from this review will be guided by the Realist and Meta-narrative Evidence Syntheses: Evolving Standards (RAMESES). This rapid realist review will support service redesign to better address the unmet palliative care needs of adults receiving haemodialysis and inform policy initiatives and education to deliver context-specific KSC across the UK and globally. ETHICS AND DISSEMINATION: This study received ethics approval from Coventry University Ethics Committee (Ref-P182536). Results will be disseminated to stakeholder groups and by means of publication in a peer-reviewed journal and presentation at international scientific conferences. PROSPERO REVIEW REGISTRATION: CRD420251000111.

Indexed as

Palliative CareRenal DialysisRenal Insufficiency, ChronicHumansResearch DesignSystematic Reviews as TopicAdult nephrologyAdult palliative careDialysisEnd stage renal failureReview

Identifiers

PMID42481190
PMCPMC13405006

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.