Evidence map›Paper›PMID 42480863›Full record

ArticleContemporary clinical trials2026

Technology-enabled collaborative care management of depression in urban and rural cancer centers: Protocol and baseline results from the SCOPE pragmatic hybrid effectiveness-implementation trial.

Jesse R Fann, Ty W Lostutter, Lydia Andris, Nicole Bates, Isaac C Rhew, Amy M Bauer, Ian M Bennett, Daniel Martin, Blair Irwin, Diane M Powers and 3 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05012124 (Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05012124 naterminatednot on this map

Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers (AKA: SUPPORTING COLLABORATIVE CARE TO OPTIMIZE PSYCHOSOCIAL ENGAGEMENT IN THE CANCER SETTING [SCOPE])

TypeinterventionalSponsorUniversity of WashingtonRan2022 to 2026Enrolled297ConditionsDepression, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid NeoplasmArmsCollaborative care, Interview or Focus Group, Media/technology Intervention with collaborative care, Survey Administration
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jesse R FannDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America; Department of Psychosocial Oncology, Fred Hutchinson Cancer Center, 825 Eastlake Ave. E., PO Box 19023, Seattle, WA 98109, United States of America. Electronic address: fann@uw.edu.
Ty W LostutterDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America; Department of Psychosocial Oncology, Fred Hutchinson Cancer Center, 825 Eastlake Ave. E., PO Box 19023, Seattle, WA 98109, United States of America.
Lydia AndrisDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America.
Nicole BatesDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America; Department of Psychosocial Oncology, Fred Hutchinson Cancer Center, 825 Eastlake Ave. E., PO Box 19023, Seattle, WA 98109, United States of America.
Isaac C RhewDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America.
Amy M BauerDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America.
Ian M BennettDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America.
Daniel MartinDepartment of Medicine, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356420, Seattle, WA 98195, United States of America.
Blair IrwinMultiCare Cancer Institute, Tacoma General Hospital, 1003 South 5th St, Tacoma, WA 98405, United States of America.
Diane M PowersDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356560, Seattle, WA 98195, United States of America.
Jourdan CruzDepartment of Psychosocial Oncology, Fred Hutchinson Cancer Center, 825 Eastlake Ave. E., PO Box 19023, Seattle, WA 98109, United States of America.
Gary HsiehDepartment of Human Centered Design & Engineering, University of Washington, 3960 Benton Lane NE, 428 Sieg Building, Seattle, WA 98195, United States of America.
James FogartyPaul G. Allen School of Computer Science & Engineering, University of Washington, Box 352350, Seattle, WA 98195, United States of America.

Funding

Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer CentersR01CA244171 · NCI · UNIVERSITY OF WASHINGTON · PI FANN, JESSE R · 2020 to 2025
$3.1M
NCI NIH HHS R01 CA244171
6 · The paper itself

Abstract

backgroundUp to 25% of people with cancer will become clinically depressed. Unfortunately, most cancer patients with depression do not receive adequate treatment. The Collaborative Care Model (CoCM) is an evidence-based system of care that can lead to sustained improvement in depression symptoms and quality of life in patients with cancer, but high fidelity implementation has been slow. We previously used a human-centered design approach to design and develop a patient- and provider-facing web platform to enhance the implementation and fidelity of CoCM for depression in patients undergoing cancer treatment. We describe the methods and baseline characteristics for a trial that compares technology-enhanced CoCM to the current CoCM approach.

methodsThe technology-enhanced CoCM system (t-CoCM) will be compared to usual CoCM (u-CoCM) in a 9-month pragmatic hybrid effectiveness-implementation randomized controlled trial among patients receiving treatment for cancer at an NCI-designated comprehensive cancer center and a community cancer center. Outcomes include clinical outcomes and CoCM fidelity as well as implementation obstacles and opportunities.

resultsThe 297 patients randomized to the study (149 t-CoCM, 148 u-CoCM) represent a diverse sample with high medical and psychiatric comorbidity. 35% had breast cancer and 43% had metastatic disease. Mean (SD) baseline Hopkins Symptom Checklist-20 (1.9 [0.7]) and Patient Health Questionnaire-9 (15.3 [4.0]) depression scores indicate significant depression symptomatology.

conclusionsThe study will provide valuable practice-based information on processes and outcomes of CoCM for depression in patients receiving acute cancer treatment and on implementation of a web platform to enhance delivery of CoCM in this setting.

trial registrationClinicaltrials.gov identifier: NCT05012124 (submitted 8/11/21).

Indexed as

DepressionNeoplasmsFemaleHumansMalePragmatic Clinical Trials as TopicQuality of LifeCancerClinical trialDepressionPragmaticTechnologyTreatment

Identifiers

PMID42480863
PMCPMC13472756

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