ArticleCell reports. Medicine2026
Association of residential greenness and Life's Essential 8 with cardiovascular disease in China.
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Article in Cell reports. Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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46 authors.
Qiuyu CaoDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Dong LiInstitute for Urban Governance and Sustainable Development, Tsinghua University, Beijing, China.
Hong LinDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Shuangyuan WangDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Mian LiDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Yonghua YuDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Ruizhi ZhengDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Yu XuDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Min XuDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Tiange WangDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Libin ZhouDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Mofan XuSchool of Resources Environment and Tourism, Capital Normal University, Beijing, China.
Yiming MuChinese People's Liberation Army General Hospital, Beijing, China.
Lulu ChenUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Tianshu ZengUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lixin ShiAffiliated Hospital of Guiyang Medical College, Guiyang, China.
Qiao ZhangAffiliated Hospital of Guiyang Medical College, Guiyang, China.
Qing SuXinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xuefeng YuTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li YanSun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Guijun QinThe First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Qin WanThe Affiliated Hospital of Southwest Medical University, Luzhou, China.
Gang ChenFujian Provincial Hospital, Fujian Medical University, Fuzhou, China.
Xulei TangThe First Hospital of Lanzhou University, Lanzhou, China.
Zhengnan GaoDalian Municipal Central Hospital, Dalian, China.
Ruying HuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Zuojie LuoThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yingfen QinThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Li ChenQilu Hospital of Shandong University, Jinan, China.
Xinguo HouQilu Hospital of Shandong University, Jinan, China.
Yanan HuoJiangxi provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Qiang LiThe Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Guixia WangThe First Hospital of Jilin University, Changchun, China.
Yinfei ZhangCentral Hospital of Shanghai Jiading District, Shanghai, China.
Chao LiuJiangsu Province Hospital on Integration of Chinese and Western Medicine, Nanjing, China.
Youmin WangThe First Affiliated Hospital of Anhui Medical University, Hefei, China.
Shengli WuKaramay Municipal People's Hospital, Karamay, Xinjiang, China.
Tao YangThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Huacong DengThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jiajun ZhaoShandong Provincial Hospital affiliated to Shandong University, Jinan, China.
Feixia ShenThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xuejiang GuThe First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Guang NingDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Jieli LuDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China. Electronic address: ljl11319@rjh.com.cn.
Weiqing WangDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China. Electronic address: wqwang61@163.com.
Yufang BiDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai Key Laboratory for Endocrine Tumor, Shanghai National Center for Translational Medicine, Shanghai Digital Medicine Innovation Center, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China. Electronic address: byf10784@rjh.com.cn.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prospective evidence linking greenness and cardiovascular disease (CVD) in rapidly urbanizing developing countries remains limited. Here, among 159,590 adults aged ≥40 years from the nationwide China Cardiometabolic Disease and Cancer Cohort with a median follow-up of 10.1 years, we examine the association between residential greenness, measured by satellite-derived normalized difference vegetation index (NDVI) within 500 m of residence, and incident CVD, and evaluate its joint effects with cardiovascular health as defined by Life's Essential 8. Individuals in the highest quartiles of contemporaneous, one-year, and cumulative NDVI consistently show lower CVD risk compared with those in the lowest quartiles, although associations vary across subpopulations. Notably, individuals with high cardiovascular health scores living in low-NDVI areas exhibit similar CVD risk to those residing in high-NDVI areas. These findings highlight the complementary importance of both green infrastructure and healthy lifestyles in reducing CVD risk in rapidly urbanizing regions of China.
Indexed as
Cardiovascular DiseasesChinaFemaleHumansMaleMiddle AgedRisk FactorsUrbanizationcardiovascular diseasecardiovascular health scorecombined effectsresidential greenness
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