Evidence map›Paper›PMID 42480118›Full record

ReviewEpigenetics2026

Decoding osteosarcoma pathogenesis: the pivotal influence of m

Chaomei Huang, Zhongyu Han, Junyan Su, Meiqi Zhang, Yumeng Lin, Haibei He, Yu Tang, Peng Guo, Yi Wang, Haoran Chen

Abstract readReview
In one paragraph

Review in Epigenetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chaomei HuangDepartment of Rehabilitation Medicine, Chengdu Xinhua Hospital Affiliated to North Sichuan Medical College, Chengdu, China.
Zhongyu HanInstitute of Nephrology, Zhongda Hospital, Southeast University, Nanjing, China.
Junyan SuDepartment of Rehabilitation Medicine, The First People's Hospital of Longquanyi District, Chengdu, China.
Meiqi ZhangCenter of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, China.
Yumeng LinDepartment of Nanjing Tongren Eye Center, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, China.
Haibei HeDepartment of Rehabilitation Medicine, Chengdu Xinhua Hospital Affiliated to North Sichuan Medical College, Chengdu, China.
Yu TangDepartment of Rehabilitation Medicine, Chengdu Xinhua Hospital Affiliated to North Sichuan Medical College, Chengdu, China.
Peng GuoDepartment of Rehabilitation Medicine, Chengdu Xinhua Hospital Affiliated to North Sichuan Medical College, Chengdu, China.
Yi WangDepartment of Rehabilitation Medicine, Chengdu Xinhua Hospital Affiliated to North Sichuan Medical College, Chengdu, China.
Haoran ChenDepartment of Rehabilitation Medicine, Chengdu Xinhua Hospital Affiliated to North Sichuan Medical College, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is the predominant primary malignant bone tumor in children and adolescents. Current treatments mainly include surgical resection combined with chemotherapy, but they still cannot effectively control tumor metastasis and recurrence, and may pose a risk of long-term complications. N6-methyladenosine (m

Indexed as

AdenosineBone NeoplasmsOsteosarcomaApoptosisCell ProliferationEpigenesis, GeneticEpitranscriptomeGene Expression Regulation, NeoplasticHumansMetabolic ReprogrammingRNA MethylationTumor MicroenvironmentAdenosineN-methyladenosinem6Ametabolic reprogrammingOsteosarcomaprogrammed cell deathtumor microenvironment

Identifiers

PMID42480118
PMCPMC13390514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.