Evidence map›Paper›PMID 42479844›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Cryo-EM reveals that

Alexander Harjung, Ember M Ruth, Mariusz Matyszewski, Jaehee Park, Caroline Knittel, Evan McCormack, Neal K Devaraj

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander HarjungDepartment of Chemistry and Biochemistry, University of California, San Diego, CA 92093.ORCID 0009-0002-4219-4686
Ember M RuthDepartment of Chemistry and Biochemistry, University of California, San Diego, CA 92093.
Mariusz MatyszewskiDepartment of Molecular Biology, School of Biological Sciences, University of California, San Diego, CA 92093.ORCID 0000-0003-1033-9270
Jaehee ParkDepartment of Chemistry and Biochemistry, University of California, San Diego, CA 92093.
Caroline KnittelDepartment of Chemistry and Biochemistry, University of California, San Diego, CA 92093.
Evan McCormackDepartment of Chemistry and Biochemistry, University of California, San Diego, CA 92093.ORCID 0000-0002-1412-9556
Neal K DevarajDepartment of Chemistry and Biochemistry, University of California, San Diego, CA 92093.ORCID 0000-0002-8033-9973

Funding

Illuminating cellular dark matter through the development of novel chemical toolsR35GM141939 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEVARAJ, NEAL KRISHNA · 2021 to 2025
$2.2M
NIGMS NIH HHS R35 GM141939
6 · The paper itself

Abstract

Bacterial tRNA-guanine transglycosylases (TGT) are essential enzymes involved in tRNA modification, contributing to the virulence of multiple pathogens. TGT from

Indexed as

Escherichia coliEscherichia coli ProteinsPentosyltransferasesRNA, TransferCryoelectron MicroscopyModels, MolecularProtein BindingEscherichia coli ProteinsPentosyltransferasesqueuine tRNA-ribosyltransferaseRNA, Transfercryo-EMposttranscriptional modificationRNARNA binding proteintransglycosylase

Identifiers

PMID42479844
PMCPMC13416341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.