Evidence map›Paper›PMID 42479731›Full record

ArticlePloS one2026

The future of births via medically assisted reproduction in Italy:Scenarios to 2050.

Alessandra Burgio, Cinzia Castagnaro, Gustavo De Santis, Daniele Vignoli, Agnese Vitali

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alessandra BurgioItalian National Institute of Statistics, Rome, Italy.
Cinzia CastagnaroItalian National Institute of Statistics, Rome, Italy.
Gustavo De SantisDepartment of Statistics, Computer Science, Applications, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0003-2058-2629
Daniele VignoliDepartment of Statistics, Computer Science, Applications, University of Florence, Florence, Italy.
Agnese VitaliDepartment of Sociology and Social Research, University of Trento, Trento, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed childbearing is increasingly common in high-income societies, contributing to rising demand for medically assisted reproduction (MAR). This paper presents nine possible scenarios of the future share of MAR births on the total number of births in Italy, a country internationally known for its latest-late mean age at childbearing. We combined the latest (2023) official data and three hypotheses on the evolution of maternal mean age at childbirth (no change, slow ageing, rapid ageing) with three hypotheses on the age-specific MAR-related fertility rates (no change, moderate increase, rapid increase). Our projections indicate that changes in the age structure of women of reproductive age will likely have a negligible effect on future MAR prevalence. In contrast, delayed childbearing and continued expansion of MAR use could raise the share of MAR births from 4.3% in 2023 to 11-12% by mid-century, with a plausible upper bound exceeding 15% under sustained trends. These results underscore the growing demographic, social and economic significance of MAR in Italy and highlight important implications for public health planning, resource allocation, and policies aimed at supporting earlier childbearing.

Indexed as

Birth RateReproductive Techniques, AssistedAdultFemaleHumansItalyMaternal AgeMiddle AgedPregnancy

Identifiers

PMID42479731
PMCPMC13387555

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.