Evidence map›Paper›PMID 42479636›Full record

ArticlePloS one2026

Lateral similarity and symmetry of biometric data from the LenStar in a population with cataract.

Achim Langenbucher, Jascha Wendelstein, Alan Cayless, Stefan Wagenpfeil, Peter Hoffmann, David Cooke, Nóra Szentmáry

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Achim LangenbucherDepartment of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.ORCID https://orcid.org/0000-0001-9175-6177
Jascha WendelsteinDepartment of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.ORCID https://orcid.org/0000-0003-4145-2559
Alan CaylessSchool of Physical Sciences, The Open University, Milton Keynes, United Kingdom.ORCID https://orcid.org/0000-0003-0779-7449
Stefan WagenpfeilInstitute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University, Homburg/Saar, Germany.ORCID https://orcid.org/0000-0002-4558-4041
Peter HoffmannAugen- und Laserklinik Castrop-Rauxel, Castrop-Rauxel, Germany.
David CookeGreat Lakes Eye Care, Saint Joseph, Michigan, United States of America.ORCID https://orcid.org/0000-0002-8126-853X
Nóra SzentmáryDepartment of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the similarity and symmetry of biometric measures between eyes in a large dataset of measurements of both eyes taken with the LenStar optical biometer.

methodsCross-sectional non-randomised study evaluating a dataset containing 13,420 bilateral LenStar 900 biometric measurements on patients without history of eye surgery or ocular pathology taken before cataract surgery, consisting of scalar parameters axial length AL, corneal thickness CCT, anterior chamber depth ACD, lens thickness LT and corneal diameter WTW. The keratometric power vector components equivalent power KEQ were assessed for similarity, and the projections of corneal astigmatism vector KC0 and KC45 were analysed for direct and mirror symmetry with respect to the vertical (sagittal) plane.

resultsMean / standard deviation (squared correlation coefficient) difference between right and left eye measures was 0.02 ± 0.31(0.95) / 0.00 ± 0.01(0.93) / 0.00 ± 0.14(0.88) / -0.01 ± 0.22(0.78) / -0.02 ± 0.17(0.87) mm for AL / CCT / ACD / LT / WTW and -0.06 ± 0.48(0.92) dioptres for KEQ. Keratometric astigmatism showed a high degree of mirror symmetry (KC45 of left eyes inverted in sign) which outperforms direct symmetry. The median deviation of the keratometric axes of both eyes considering mirror symmetry was 15 degrees compared to 29 degrees for direct symmetry.

conclusionsIn most cases, biometric measures match between eyes of a subject, but there are rare situations with large deviations between eyes. Keratometric astigmatism exhibits mirror symmetry. In most cases the biometric measures from the contralateral eye could be used where biometry is unavailable or to double-check before cataract surgery.

Indexed as

BiometryCataractAgedAnterior ChamberAstigmatismCataract ExtractionCorneaCross-Sectional StudiesFemaleHumansMaleMiddle Aged

Identifiers

PMID42479636
PMCPMC13387570

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