Evidence map›Paper›PMID 42479342›Full record

ArticleHead and neck pathology2026

A Deep Learning AI Model for Histopathological Diagnosis and Grading of Mucoepidermoid Carcinoma of Salivary Glands (Diagnostic Accuracy Study).

Doha Ibrahim Abd El Ati, Safa Fathy, Hamza EmadElDin Hamza, Shymaa Hamza

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Article in Head and neck pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Doha Ibrahim Abd El AtiDepartment of Oral and Maxillofacial Pathology, Faculty of Dentistry, Cairo University, Cairo, Egypt. doha-ibrahem@dentistry.cu.edu.eg.ORCID http://orcid.org/0009-0004-4231-3555
Safa FathyDepartment of Oral and Maxillofacial Pathology, Faculty of Dentistry, Cairo University, and School of Dentistry, Newgiza University, Cairo, Egypt.
Hamza EmadElDin HamzaDepartment of Artificial Intelligence, Faculty of Computing and Artificial Intelligence, Cairo University, Cairo, Egypt.
Shymaa HamzaDepartment of Oral and Maxillofacial Pathology, Faculty of Dentistry, Cairo University, and School of Dentistry, Newgiza University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to evaluate the effectiveness of deep learning AI model in the diagnosis and grading of mucoepidermoid carcinoma.

methodsWe developed a multiple instance learning based-deep learning model which consisted of two modules. One to perform slide-level classification of whole slide images into mucoepidermoid carcinoma and non-mucoepidermoid carcinoma classes and the second one to perform grading into low, intermediate, and high grades. A total of 194 whole slide images were included in the study. Of these, 92 corresponded to mucoepidermoid carcinoma, while the remaining 102 represented non-mucoepidermoid carcinoma cases.

resultsOur results showed that the classification model achieved 90.62% accuracy, 90.62% macro F1 score, 90.60% weighted F1 score, 91.67% macro precision, 91.18% macro recall. The grading model achieved an accuracy of 73.3%, weighted F1-score of 73.9%, weighted precision of 76.1% and weighted recall of 73.3%.

conclusionThe proposed deep learning classification model achieved promising performance in differentiating mucoepidermoid carcinoma cases. However, the grading model achieved an overall accuracy of 73.3%. Thus, depending on AI solely is still questionable, however it can be used to augment the work of the pathologist.

Indexed as

Carcinoma, MucoepidermoidDeep LearningSalivary Gland NeoplasmsHumansMultiple-Instance Learning AlgorithmsNeoplasm GradingClassificationDeep learningGradingMucoepidermoid carcinoma

Identifiers

PMID42479342
PMCPMC13388593

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.