Evidence map›Paper›PMID 42479331›Full record

ArticleNeurocritical care2026

Implantation Standards for Intracranial Multimodal Monitoring (Neurocore-iMMM): An International Delphi Consensus.

Sami Barrit, Trinity Pate, Maria A Poca, Allen Waziri, P David Adelson, András Büki, Antoine Devalckeneer, Ramon Navarro, John Kanter, David O Okonkwo and 7 more

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Article in Neurocritical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Sami BarritDepartment of Neurological Surgery, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA, 90095, USA. sami.barrit@ucsf.edu.ORCID http://orcid.org/0000-0002-9073-4504
Trinity PateSciense, New York, NY, 10004, USA.
Maria A PocaDepartment of Neurosurgery, Vall d'Hebron University Hospital, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Allen WaziriiCE Neurosystems, 4301 50th St NW, Suite 317, Washington, DC, 20016, USA.
P David AdelsonDepartment of Neurosurgery, WVU Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA.
András BükiDepartment of Neurosurgery, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Antoine DevalckeneerDepartment of Neurosurgery, CHU Lille, Université de Lille, Lille, France.
Ramon NavarroDepartment of Neurosurgery, James Cook University, Townsville, Australia.
John KanterDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
David O OkonkwoDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Bart DepreitereNeurosurgery, University Hospitals Leuven, Leuven, Belgium.
Daniel PinggeraDepartment of Neurosurgery, Medical University Innsbruck, Innsbruck, Austria.
Jonathon J ParkerDepartment of Neurosurgery, Mayo Clinic, Phoenix, USA.
The Neurocore-iMMM Study Group
Nicolas EngrandDepartment of NeuroCU-Anesthesiology, Rothschild Foundation Hospital, 75019, Paris, France.
Salim El HadweSciense, New York, NY, 10004, USA.
Alfonso LagaresDepartment of Neurosurgery, Hospital Universitario 12 de Octubre, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveIntracranial multimodal monitoring (iMMM) use is expanding, yet inconsistent documentation of the implantation procedure prevents data comparability and accurate safety profiling. We aimed to establish implantation standards defining which variables require documentation and at what specificity.

methodsWe conducted a three-round modified Delphi (May-August 2025) with an international panel of 82 experts with hands-on implantation experience. We investigated items common to the foundational Neurocore-iMMM consensus to test agreement between panels. Thresholds: ≥ 75% strong agreement, 66-74% moderate, and < 50% no consensus.

resultsRetention was 72% through all rounds. Of 120 items (47% participant-proposed), 57 achieved consensus. Agreed-upon standards include probe placement documentation specifying tissue type (perilesional or normal-appearing), approach (image-guided or standardized), and post-placement imaging verification (99%); complication reporting specifying misplacement (98%), postoperative hemorrhage with location (99%), and CNS infection with colonization distinguished from infection by CSF cell count and mandatory culture of withdrawn material (95%); adverse event subcategorization of accuracy drift into probe displacement, calibration loss, and signal instability (91%); and documentation of leveling reference for fluid-filled lines (78%), fixation device configuration (77%), and recalibration protocol (76%). On 25 of 29 items shared with the foundational consensus, the two independent panels reached concordant agreement.

conclusionsAligned with NIH Common Data Elements, these implantation standards specify documentation from anatomical targeting designation to adverse event subcategorization for cross-center comparison, providing the item-level foundation from which reporting criteria can be operationalized and an implementation-ready framework for multicenter neurocritical care databases and monitoring-guided therapy trials.

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ConsensusDelphiImplantationIntracranial monitoringStandards

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.