ArticleCancer science2026
MEN1 Deficiency Drives Lung Cancer Progression via Activation of MMP10-Mediated Angiogenesis.
Article in Cancer science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Angiogenesis is essential for tumor progression, MEN1 gene encodes the menin protein, which is known as a tumor suppressor in lung tissue. Our previous study have shown that vascular density is significantly increased in menin-deficient lung cancer, suggesting that menin deficiency may promote the malignant progression of lung cancer by enhancing angiogenesis. However, whether menin play an important role in angiogenesis of lung cancer and the underlying mechanisms remain unclear. In this study, lung-specific Kras
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