Evidence map›Paper›PMID 42479072›Full record

ArticleEuropean journal of applied physiology2026

Lung function decline after mountain ultra-marathon is accompanied by reduced inspiratory pressure but not by detectable changes in CC16.

Antoine Raberin, Bastien Krumm, Tom Citherlet, Guia Tagliapietra, Tadej Debevec, Vincent Pialoux, Grégoire P Millet

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Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Antoine Raberin *Institute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, CH-1015, Switzerland. antoine.raberin@unil.ch.ORCID http://orcid.org/0000-0001-5032-8301
Bastien Krumm *Institute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, CH-1015, Switzerland.
Tom CitherletInstitute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, CH-1015, Switzerland.
Guia TagliapietraInstitute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, CH-1015, Switzerland.
Tadej DebevecFaculty of Sports, University of Ljubljana, Ljubljana, Slovenia.
Vincent PialouxAtherosclerosis, Thrombosis and Physical Activity Team, Interuniversity Laboratory of Human Movement Biology UR7424, Université Claude Bernard Lyon 1, Univ Lyon, Lyon, France.
Grégoire P MilletInstitute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, CH-1015, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMountain ultra-marathons (MUM) impose multiple stressors on pulmonary function inducing risk of airway epithelial damage. This study aimed to assess the magnitude of pulmonary function changes and the associated risks of airway damage induced by such a race.

methodsThirteen volunteers completed the MUM (330 km, 24,000 m elevation gain). Pulmonary function was assessed using standardized procedures before (pre-) and within 1 h after (post-) the race. Assessments included forced inhalation and exhalation maneuvers, as well as maximal inspiratory pressure (MIP) measurements. Venous blood samples were collected for the analysis of plasma club cell secretory protein 16 (CC16). Blood volume was determined using the carbon monoxide rebreathing method.

resultsFrom pre- to post-, forced vital capacity (FVC) (-7.5%, p = 0.001), forced expiratory volume in 1 s (FEV

conclusionThe acute negative impact of MUM on pulmonary function has been confirmed. The extent of this impairment appears to be proportional to race duration. Biomarker analysis suggests that airway epithelial integrity remains preserved. The reduced pulmonary function could be due to respiratory muscle fatigue.

Indexed as

InhalationLungMarathon RunningUteroglobinAdultAltitudeFemaleForced Expiratory VolumeHumansMaleRespiratory Function TestsVital CapacitySCGB1A1 protein, humanUteroglobinAltitudeEnvironmental physiologyPulmonary systemUltra-enduranceUltra-trail

Identifiers

PMID42479072

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.