Evidence map›Paper›PMID 42479071›Full record

ArticleEuropean journal of applied physiology2026

Effects of six weeks of hypoxia and hypoxic SIT on oxidative stress and myokine responses in skeletal muscle of high-fat-fed ApoE

Yangwenjie Wang, Jessica Lavier, Linjia Wang, Weicheng Hua, Hao Wei, Changle Zhao, Maxime Pellegrin, Grégoire P Millet, Ying Zhang

Abstract read
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In one paragraph

Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yangwenjie WangCollege of Sports and Health, Shandong Sport University, Jinan, 250102, China.
Jessica LavierInstitute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, 1015, Lausanne, Switzerland.
Linjia WangSchool of Sport Science, Beijing Sport University, Beijing, 100084, China.
Weicheng HuaSchool of Sport Science, Beijing Sport University, Beijing, 100084, China.
Hao WeiSchool of Sport Science, Beijing Sport University, Beijing, 100084, China.
Changle ZhaoCollege of Sports and Health, Shandong Sport University, Jinan, 250102, China.
Maxime PellegrinDivision of Angiology, Heart and Vessel Department, Lausanne University Hospital (CHUV), 1011, Lausanne, Switzerland.
Grégoire P MilletInstitute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, 1015, Lausanne, Switzerland. gregoire.millet@unil.ch.
Ying ZhangSchool of Sport Science, Beijing Sport University, Beijing, 100084, China. zhyi9256@bsu.edu.cn.ORCID http://orcid.org/0009-0002-7786-3261

Funding

Fundamental Research Funds for the Central Universities 20211009
6 · The paper itself

Abstract

Atherosclerosis-induced oxidative stress drives skeletal muscle myopathy in peripheral artery disease, yet the combined effects of hypoxia and hypoxia sprint interval training (SIT) remain unclear. The present study was designed to evaluate how a six-week regimen of hypoxia exposure and SIT influences redox balance and myokine production in the skeletal muscle of high-fat diet (HFD) (21% fat, 1.5% (w/w) cholesterol; 43% (w/w) sucrose-free carbohydrate, 4.554 kcal/g)-fed atherosclerotic ApoE

Indexed as

High-Intensity Interval TrainingHypoxiaMuscle, SkeletalOxidative StressPhysical Conditioning, AnimalAnimalsApolipoproteins EDiet, High-FatMaleMiceMice, Inbred C57BLMyokinesReactive Oxygen SpeciesApolipoproteins EMyokinesReactive Oxygen SpeciesAtherosclerosisHypoxiaMyokine productionOxidative stressSITSkeletal muscle

Identifiers

PMID42479071

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.