Evidence map›Paper›PMID 42479069›Full record

Trial reportEuropean journal of applied physiology2026

Skeletal muscle twitch relaxation kinetics following heat stress endurance: carbohydrate versus placebo.

Camila Nassif, Jack Cannon, Frank E Marino

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Camila NassifSchool of Allied Health, Exercise and Sports Sciences, Charles Sturt University, NSW, Orange, 2800, Australia.
Jack CannonSchool of Allied Health, Exercise and Sports Sciences, Charles Sturt University, NSW, Orange, 2800, Australia.
Frank E MarinoSchool of Rural Medicine, Charles Sturt University, Orange, NSW, 2800, Australia. fmarino@csu.edu.au.ORCID http://orcid.org/0000-0001-8352-6208

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare post-exercise twitch contractile properties and M-wave characteristics after 60-km self-paced cycling in the heat following placebo (PLA) or 6% carbohydrate (CHO) ingestion as beverages or capsules.

methodsTen well-trained male cyclists completed five randomised Latin-square trials: water (H₂O), CHO beverage (CHO

resultsPerformance time (p = 0.336) and time to task failure (p = 0.394) did not differ between conditions. iEMG increased during the 20% MVC in all trials (all p < 0.0001). There were no condition × time interactions for MVC, VA, M-wave amplitude (all p ≥ 0.335), or twitch contractile variables (all p ≥ 0.115). Time effects were observed for rate of relaxation, which decreased in all trials (p = 0.0302 to p = 0.000239), contraction duration, which increased in all trials (p = 0.0412 to p = 0.000091), and half-relaxation time, which increased in H₂O, PLA

conclusionsProlonged self-paced cycling in the heat produced a reproducible neuromuscular response dominated by slowed twitch relaxation. However, 6% CHO ingestion did not clearly attenuate these changes compared with PLA, suggesting that the principal impairment reflected exercise and heat load rather than CHO availability or delivery mode.

Indexed as

Dietary CarbohydratesHeat-Shock ResponseMuscle RelaxationMuscle, SkeletalPhysical EnduranceAdultHot TemperatureHumansMaleMuscle ContractionDietary Carbohydrates

Identifiers

PMID42479069
PMCPMC13633997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.