Evidence map›Paper›PMID 42478846›Full record

ArticlemBio2026

A two-component regulatory system mediates quorum sensing-dependent morphology and motility transitions in the archaeon

Jacob A Cote, Priyanka Chatterjee, Marco Garcia, Ran Tao, Arnold J T M Mathijssen, Mechthild Pohlschroder

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jacob A CotePerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-4840-7489
Priyanka ChatterjeePerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1608-7190
Marco GarciaDepartment of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0009-0000-4225-7486
Ran TaoDepartment of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0009-0001-7720-6459
Arnold J T M MathijssenDepartment of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-9577-8928
Mechthild PohlschroderPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7729-1342

Funding

TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM007229 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1985 to 2023
$14.0M
Cell-cell signaling in archaea: How Haloferax volcanii talk to each otherF31AI181536 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHATTERJEE, PRIYANKA · 2024 to 2025
$90k
Charles E. Kaufman Foundation KA2022-129523, KA2024-144001Merck/PennFERBS fellowshipNational Science Foundation CBET-2542731National Science Foundation UPenn MRSEC DMR-2309043National Science Foundation UPenn NSF-MBC2222076National Science Foundation Graduate Research Fellowship ProgramNIAID NIH HHS F31 AI181536NIGMS NIH HHS T32 GM007229NIH HHS 1F31AI181536-01NIH HHS UPenn T32 GM007229Research Corporation for Science Advancement CS-CSA-2026-125University of Pennsylvania Research Fund
6 · The paper itself

Abstract

Quorum sensing (QS) enables microorganisms-including bacteria, eukaryotes, and viruses-to coordinate collective behaviors in response to population density. Despite their ecological and evolutionary significance, QS mechanisms in Archaea remain poorly characterized. The halophilic archaeon

Indexed as

Haloferax volcaniiLocomotionQuorum SensingArchaeal ProteinsGene Expression Regulation, ArchaealArchaeal ProteinsarchaeaHaloferax volcaniimorphologymotilityquorum sensingtwo-component regulatory systems

Identifiers

PMID42478846
PMCPMC13464002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.