Evidence map›Paper›PMID 42478366›Full record

ArticleCirculation. Cardiovascular imaging2026

RACI: A Novel Prognostic Marker in Functional Tricuspid Regurgitation.

Robert S Zhang, Giorgia Falco, Emily Li, Pablo Villar-Calle, Mahniz Reza, Edmund Naami, Elizabeth Manowitz, Prianca Tawde, Radhika Narasimhan, Mojdeh Yadollahikhales and 4 more

Abstract read
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In one paragraph

Article in Circulation. Cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Robert S Zhang *Division of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.ORCID 0000-0002-7946-6094
Giorgia Falco *Division of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.
Emily LiDivision of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.
Pablo Villar-CalleDivision of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.ORCID 0000-0001-7249-7667
Mahniz RezaDivision of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.
Edmund NaamiDivision of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.
Elizabeth ManowitzDivision of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.
Prianca TawdeDepartment of Medicine (P.T., R.N., M.Y.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.ORCID 0000-0002-6338-2224
Radhika NarasimhanDepartment of Medicine (P.T., R.N., M.Y.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.ORCID 0000-0003-1626-1320
Mojdeh YadollahikhalesDepartment of Medicine (P.T., R.N., M.Y.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.ORCID 0009-0000-8755-7730
Lisa Q RongDepartment of Anesthesiology (L.Q.R.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.ORCID 0000-0003-0982-7154
Arindam RoyChoudhuryDivision of Biostatistics and Epidemiology, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY (A.R.).ORCID 0009-0000-4306-0570
Jonathan W WeinsaftDivision of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.
Jiwon KimDivision of Cardiology (R.S.Z., G.F., E.L., P.V.-C., M.R., E.N., E.M., J.W.W., J.K.), Weill Cornell Medicine, NewYork-Presbyterian Hospital.ORCID 0000-0002-8420-8604

Funding

Advanced CMR Tissue-Based Prediction of Right Ventricular Dysfunction and Revascularization ResponseK23HL140092 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, JIWON · 2018 to 2022
$847k
NHLBI NIH HHS K23 HL140092
6 · The paper itself

Abstract

backgroundRight atrioventricular coupling index (RACI), defined as the ratio of right atrial (RA) to right ventricular (RV) end-diastolic volume on cardiac magnetic resonance, is a novel parameter that reflects RA-RV hemodynamic interplay. Its prognostic value in functional tricuspid regurgitation (TR) is unknown.

methodsThis study included 633 consecutive patients with moderate or greater functional TR undergoing cardiac magnetic resonance. Patients were stratified into 2 groups based on the optimal cutoff by the Youden index (normal: RACI<0.62 versus high: RACI≥0.62). The primary outcome was all-cause mortality.

resultsPatients with high RACI (n=147) were older (74.1±10.7 years versus 60.6±16.1 years,

conclusionsRACI is a novel parameter that effectively integrates RA and RV remodeling, and independently predicts all-cause mortality in functional TR. Incorporating RACI into clinical assessment may help with improving risk stratification and guiding the timing of intervention in patients with functional TR.

Indexed as

Atrial Function, RightMagnetic Resonance Imaging, CineStroke VolumeTricuspid ValveTricuspid Valve InsufficiencyVentricular Function, RightAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesRisk Factorshemodynamicsmagnetic resonance imagingprognosisrisktricuspid valve insufficiency

Identifiers

PMID42478366
PMCPMC13543000

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.