ArticleZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2026
[Effects of exercise interventions on anxiety and depressive symptoms in patients with fibromyalgia syndrome: a meta-analysis].
Article in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
objectivesTo systematically evaluate the therapeutic effects of exercise interventions on anxiety and depressive symptoms in patients with fibromyalgia syndrome (FMS), compare the differential efficacy of various exercise modalities, and provide evidence-based guidance for optimizing individualized exercise prescriptions in clinical practice.
methodsA comprehensive literature search was conducted in CNKI, VIP, Wanfang Data, SinoMed, Web of Science, PubMed, Cochrane Library, and Embase from inception to August 25, 2025. Study selection followed the PICOS framework, and methodological quality was assessed using the Cochrane risk of bias tool. Conventional pairwise meta-analysis was performed to evaluate the overall effect of exercise interventions, with heterogeneity assessed via the
resultsA total of 30 articles (comprising 33 studies) with 1844 participants were included. Pairwise meta-analysis showed that, compared with control groups, exercise interventions significantly improved anxiety symptoms (SMD=-0.407, 95%CI: -0.515--0.298,
conclusionsExercise interventions are safe and effective in ameliorating anxiety and depressive symptoms in patients with FMS. Mind-body exercise and aerobic exercise may be the optimal choices for anxiety symptoms and depressive symptoms, respectively, and their efficacy is associated with exercise prescription parameters.
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