Evidence map›Paper›PMID 42477522›Full record

ArticleBMC genomics2026

Multi-omics integration of F

Guankai Zhao, Yanzhen Yin, Junzhao Han, Jianmei Chen, Mengyu Li, Xiangyu Han, Jinfeng Ma, Jianghui Yu, Jin Zhou, Chifeng Chen and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guankai Zhao *Key Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Yanzhen Yin *Key Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Junzhao HanKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Jianmei ChenKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Mengyu LiKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Xiangyu HanKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Jinfeng MaKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Jianghui YuKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Jin ZhouKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Chifeng ChenKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Ruihua HuangKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Pinghua LiKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China.
Qingbo ZhaoKey Laboratory of Pig Genetic Resources Evaluation and Utilization, Ministry of Agriculture and Rural Affairs (Nanjing), Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, PR China. qingbo_zhao@aliyun.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory diseases significantly impair pig growth performance by reducing average daily gain and feed conversion efficiency. Pneumonia lesion score (PLS) is a reliable phenotypic indicator for detecting respiratory issues in pig herds, including subclinical infections that often remain undiagnosed. In this study, PLS data was collected from 327 Large White pigs, and whole-genome resequencing (WGS) was performed. Lung tissue samples from pigs with extremely high and low PLS values were subjected to transcriptomic sequencing and Fixation Index (F

resultsBy integrating F

conclusionsOverall, this study provides novel insights into the genetic mechanisms underlying porcine lung lesions and offers a foundation for breeding strategies aimed at improving respiratory disease resistance and herd health.

Indexed as

Gene Expression ProfilingGenome-Wide Association StudyPneumoniaSwine DiseasesTranscriptomeAnimalsMultiomicsPolymorphism, Single NucleotideSwineGWASPigPneumonia lesion scoresTranscriptomeTWAS

Identifiers

PMID42477522
PMCPMC13670770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.