Evidence map›Paper›PMID 42477342›Full record

ArticleNature communications2026

Ligand relay catalysis enables asymmetric migratory dearomative annulation of N-heteroarenes.

Zhiyong Song, Xinyu Li, Xinchen Wang, Asif Rasool, You Wang, Shaolin Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiyong SongState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China.
Xinyu LiState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China.
Xinchen WangState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China.
Asif RasoolState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China.
You WangState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China. wangyou@nju.edu.cn.ORCID http://orcid.org/0000-0001-6470-4646
Shaolin ZhuState Key Laboratory of Coordination Chemistry, Engineering Research Center of Photoresist Materials Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China. shaolinzhu@nju.edu.cn.ORCID http://orcid.org/0000-0003-1516-6081

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22271143National Natural Science Foundation of China (National Science Foundation of China) 22271146National Natural Science Foundation of China (National Science Foundation of China) 22571152
6 · The paper itself

Abstract

Chiral N-spiroheterocycles are privileged yet synthetically challenging scaffolds for ligands, functional materials, and drug discovery. Here we show a cobalt-catalyzed asymmetric migratory dearomative annulation of electron-deficient N‑heteroarenes for their construction. The success of this transformation hinges on a dynamic ligand relay catalysis strategy, wherein two distinct ligands work in tandem: one facilitates a 1,4-cobalt/hydride shift, and the other governs the enantioselective dearomative annulation, delivering chiral N-spiroheterocycles with high efficiency and selectivity.

Identifiers

PMID42477342
PMCPMC13500722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.