ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Development and external validation of the NEO-READY model to predict date of discharge among premature neonatal intensive care patients.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo develop a parsimonious, interpretable, and accurate model for predicting discharge for premature infants in the NICU-a model suitable for prospective evaluation and integration into clinical workflows. STUDY
designUsing routinely available electronic health record data, we developed and validated NEOnatal Reliable Estimation of Approaching Discharge in Young Infants (NEO-READY), a daily-updating model that predicts the likelihood of discharge within 5 days for premature infants.
resultsData from 702 infants were used to develop the model, and data from 201 infants were used for temporal external validation. The model included 13 predictors and two interaction terms and demonstrated excellent discrimination across development (AUC = 0.88, 95% CI 0.87-0.90) and validation (0.90, 0.88-0.91) cohorts.
conclusionThis work represents step 1 toward our long-term goal: integrating the NEO-READY model into clinical workflows as part of a comprehensive strategy to improve discharge preparedness, reduce discharge delays, and optimize NICU resources.
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