ArticleThe Journal of veterinary medical science2026
Clinical evaluation of plasma D-dimer concentrations as a marker for thromboembolism in cattle with inflammation.
Article in The Journal of veterinary medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Plasma D-dimer concentrations were measured in 15 cases with thromboembolism and 19 cases without thromboembolism among bovine patients with inflammatory diseases, and the clinical usefulness of plasma D-dimer as a thromboembolic marker was evaluated. No significant difference in plasma D-dimer concentrations was observed between the two groups. A receiver operating characteristic curve was created, and with a plasma D-dimer cutoff value of 0.38 mg/L, the sensitivity and the specificity were 86.7% and 31.2%, respectively. Furthermore, there was a large variability in plasma D-dimer concentrations in cases with thromboembolism. These results indicate that the measurement of plasma D-dimer alone in the diagnosis of thromboembolism in cattle does not have sufficient specificity. In a multivariate logistic regression analysis regarding thromboembolism detection, platelet count was significant in the likelihood ratio test, suggesting that considering platelet count in addition to plasma D-dimer may allow for the detection of thromboembolism.
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