ArticleThe Journal of veterinary medical science2026
Pathological features of fibrous proliferative lesions of the vagina in dogs.
Article in The Journal of veterinary medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical, histological, and immunohistochemical features of 26 fibrous proliferative lesions in the vagina of 14 female dogs (13 intact and 2 neutered) were examined. These lesions presented as nodular or pedunculated masses. Histopathological examination revealed that all lesions consisted of spindle- and stellate-shaped cells with mild atypia, collagenous stroma, and blood vessels. Mitotic figures were rare. The number of blood vessels was significantly greater in pedunculated masses than in nodular masses. Immunohistochemically, spindle- and stellate-shaped cells were positive for progesterone receptor in all 26 lesions, estrogen receptor in 5 of 26 lesions, desmin in 20 of 26 lesions, and α-smooth muscle actin (αSMA) in 8 of 26 lesions. Lesions in neutered dogs exhibited lower progesterone receptor expression and higher estrogen receptor expression than those in intact females. No significant differences in desmin or αSMA expression were observed between the two groups. These findings suggest that the fibrous proliferative lesions in the canine vagina described in this study may represent progesterone-associated benign proliferative changes composed of myofibroblasts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.