Evidence map›Paper›PMID 42475942›Full record

ArticleAddictive behaviors2026

Emotional urgency and lack of perseverance are linked to anxiety sensitivity and improve during early recovery from opioid use disorder.

Breanna A McNaughton-Long, Abigail J Pleiman, Carmen Buchfink, Chrysantha B Davis, Rayus Kuplicki, Martin P Paulus, Hung-Wen Yeh, Maëlle C M Gueguen, Jennifer L Stewart

Abstract read
In one paragraph

Article in Addictive behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Breanna A McNaughton-LongLaureate Institute for Brain Research, Tulsa OK, USA. Electronic address: Breanna.McNaugh-Long@creekhealth.org.
Abigail J PleimanLaureate Institute for Brain Research, Tulsa OK, USA; Department of Psychology, Louisiana State University, Baton Rouge, LA, USA. Electronic address: apleim1@lsu.edu.
Carmen BuchfinkLaureate Institute for Brain Research, Tulsa OK, USA. Electronic address: sdcarmenschutte@student.rsu.edu.
Chrysantha B DavisLaureate Institute for Brain Research, Tulsa OK, USA; Department of Psychology, University of Colorado Denver, Denver, CO, USA. Electronic address: chrysantha.davis@ucdenver.edu.
Rayus KuplickiLaureate Institute for Brain Research, Tulsa OK, USA. Electronic address: rkuplicki@laureateinstitute.org.
Martin P PaulusLaureate Institute for Brain Research, Tulsa OK, USA; Department of Community Medicine, University of Tulsa, Tulsa OK, USA. Electronic address: mpaulus@laureateinstitute.org.
Hung-Wen YehLaureate Institute for Brain Research, Tulsa OK, USA; Children's Mercy Research Institute, Kansas City, MO, USA; University of Missouri Kansas City School of Medicine, Kansas City, MO, USA. Electronic address: hyeh@laureateinstitute.org.
Maëlle C M GueguenLaureate Institute for Brain Research, Tulsa OK, USA; Oxley College of Health and Natural Sciences, University of Tulsa, Tulsa OK, USA. Electronic address: mgueguen@laureateinstitute.org.
Jennifer L StewartLaureate Institute for Brain Research, Tulsa OK, USA; Department of Community Medicine, University of Tulsa, Tulsa OK, USA. Electronic address: jstewart@laureateinstitute.org.

Funding

The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)P20GM121312 · NIGMS · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI MARTIN P. PAULUS · 2017 to 2026
$23.7M
Plasticity of Aversive Salience in Opioid Use DisorderR01DA050677 · NIDA · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI STEWART, JENNIFER LORRAINE · 2021 to 2025
$3.0M
NIDA NIH HHS R01 DA050677NIGMS NIH HHS P20 GM121312
6 · The paper itself

Abstract

Few studies have identified how facets of impulsivity relate to recovery in opioid use disorder (OUD). Treatment-enrolled individuals with OUD (n = 167) and healthy controls (CTL; n = 46) completed the Urgency, Premeditation, Perseverance, Sensation Seeking, Positive Urgency (UPPS-P) Impulsive Behavior Scale along with demographic and clinical measures at visit 1. Over the next three months, abstinence and return to use were documented for participants with OUD (via self-report, alcohol breathalyzer, urine drug screen, and secondary contact communication). Participants with OUD who returned to use (n = 59) did not complete further study visits, whereas those who remained abstinent (n = 43) and CTL (n = 36) completed the UPPS-P at three additional visits. Group analyses compared: (1) OUD (including the two subgroups) and CTL on visit 1 UPPS-P scores; and (2) abstinent OUD and CTL groups on UPPS-P scores across four visits. Regressions examined associations between visit 1 UPPS-P scores and OUD demographic and clinical characteristics. Results indicated that: (1) participants with OUD reported higher visit 1 scores than CTL on all five UPPS-P facets (none of which differentiated OUD subgroups); (2) within the OUD group, greater anxiety sensitivity severity was associated with higher Positive and Negative Urgency and Lack of Perseverance scores (argued to reflect heightened arousal in common); and (3) Positive and Negative Urgency and Lack of Perseverance scores decreased for participants with OUD who remained abstinent (but not CTL) over time. While heightened impulsivity may not be associated with return to substance use, individuals report decreased emotional urgency and increased perseverance during early addiction recovery.

Indexed as

AnxietyEmotionsImpulsive BehaviorOpioid-Related DisordersAdultCase-Control StudiesFemaleHumansMaleMiddle AgedAnxiety sensitivityCravingImpulsivityNegative urgencyOpioid use disorderPositive urgency

Identifiers

PMID42475942
PMCPMC13420875

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.