Evidence map›Paper›PMID 42474940›Full record

ArticleJournal of occupational rehabilitation2026

Cost-Effectiveness of the STEPS Work Participation Program Compared to Usual Care, for Cancer Survivors: An Economic Evaluation Alongside a Randomized Controlled Trial.

Johanna M van Dongen, Amber D Zegers, Pieter Coenen, Saskia F A Duijts, Ute Bültmann, Nina Bijker, Lisette M van Maurik, Liesbeth M Veenendaal, Ingrid E A M van Loon, Wouter K G Leclercq and 18 more

Abstract read
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In one paragraph

Article in Journal of occupational rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Johanna M van Dongen *Department of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Amber D Zegers *Department of Public and Occupational Health, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Pieter CoenenDepartment of Public and Occupational Health, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Saskia F A DuijtsDepartment of Public and Occupational Health, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Ute BültmannDepartment of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Nina BijkerDepartment of Radiation Oncology, Amsterdam UMC, Amsterdam, The Netherlands.
Lisette M van MaurikDepartment of Radiation Oncology, Amsterdam UMC, Amsterdam, The Netherlands.
Liesbeth M VeenendaalDepartment of Surgical Oncology, Alexander Monro Hospital, Bilthoven, The Netherlands.
Ingrid E A M van LoonDepartment of Obstetrics and Gynecology, Amphia Hospital, Breda, The Netherlands.
Wouter K G LeclercqDepartment of General Surgery, Máxima Medical Center, Veldhoven, The Netherlands.
Loes JanssenDepartment of General Surgery, Máxima Medical Center, Veldhoven, The Netherlands.
Peter W PlaisierDepartment of Surgery, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
Karin H HerbschlebDepartment of Medical Oncology, Antonius Hospital, Nieuwegein, The Netherlands.
Iris C M van der PloegDepartment of Surgical Oncology, Netherlands Cancer Institute Antoni Van Leeuwenhoek, Amsterdam, The Netherlands.
Marieke E StraverDepartment of Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
Clasien BlomDepartment of Gynecological Oncology, Haaglanden Medical Cancer Center, Antoniushove, The Hague, The Netherlands.
Gabriëlla de BoerDepartment of Gynecological Oncology, Haaglanden Medical Cancer Center, Antoniushove, The Hague, The Netherlands.
Anne-Marie DietvorstDepartment of Medical Oncology, Het Van Weel Bethesda Ziekenhuis, Dirksland, The Netherlands.
Mathijs P HendriksDepartment of Medical Oncology, Northwest Clinics, Alkmaar, The Netherlands.
Jacqueline M TrompDepartment of Medical Oncology, Amsterdam UMC, Amsterdam, The Netherlands.
Baukje FlamelingDepartment of Medical Oncology, OLVG Hospital, Amsterdam, the Netherlands.
Myrella VlenterieDepartment of Internal Medicine, Gelre Hospitals, Apeldoorn, The Netherlands.
Martine F ThijsDepartment of Medical Oncology, Ikazia Hospital, Rotterdam, The Netherlands.
Myra van LindeDepartment of Medical Oncology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Christianne A R LokCenter of Gynaecologic Oncology Amsterdam, Amsterdam, The Netherlands.
Esther M K WitDepartment of Urology, Netherlands Cancer Institute Antoni Van Leeuwenhoek, Amsterdam, The Netherlands.
Eva SwartNetherlands Cancer Institute Antoni Van Leeuwenhoek, Amsterdam, The Netherlands.
Allard J van der BeekDepartment of Public and Occupational Health, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. a.vanderbeek@amsterdamumc.nl.

Funding

KWF Kankerbestrijding 11558
6 · The paper itself

Abstract

purposeMany people diagnosed with cancer are of working age and experience challenges returning to and retaining-paid work. Existing interventions to support return to work have shown mixed effectiveness, and their cost-effectiveness is often unknown. The STEPS work participation program, based on the Stages of Change, aims to support employed cancer survivors in work resumption and retention. This study evaluated its cost-effectiveness compared to usual care.

methodsAn economic evaluation was conducted alongside a 12-month multi-center randomized controlled trial in the Netherlands. Employed cancer survivors were randomized to STEPS (n = 123) or usual care (n = 116). Quality-adjusted life years (QALYs) were estimated using the EQ-5D-5L questionnaire. Costs were assessed from a societal perspective. Analyses followed the intention-to-treat principle, were conducted using seemingly unrelated regression adjusted for baseline utility and costs, with uncertainty assessed using bootstrapping.

resultsParticipants in the STEPS group accrued marginally more QALYs than those receiving usual care (adjusted mean difference: 0.004; 95%CI: - 0.018 to 0.025), but this difference was neither statistically significant nor clinically relevant. Total societal costs were higher in the STEPS group than in usual care, with an adjusted mean difference of €2933 (95%CI: - €2735 to €8600). The probability of STEPS being cost-effective compared to usual care was 0.17 at a willingness-to-pay of €20,000/QALY, increasing only to 0.21 at €80,000/QALY. Sensitivity analyses confirmed these findings.

conclusionThe STEPS program cannot be considered cost-effective compared to usual care and is therefore not recommended for implementation in its current form.

Indexed as

Cancer survivorsCost-effectiveness analysisRandomized controlled trialReturn to workWork participationWork reintegrationWork retention

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.