Evidence map›Paper›PMID 42474782›Full record

ArticleTropical animal health and production2026

Influence of genomic retained heterosis on lactation persistence and tropical resilience: leveraging joint-model GWAS to quantify non-additive variance in India's Karan Fries population.

Ishmeet Kumar, Jayesh Vyas, Asad Khan, Gargi Ramola, I Ilayaraja, Lal Muansangi, Anil Chitra, Pritam Pal, Ritik Kumar Singh, M L Kamboj and 3 more

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Article in Tropical animal health and production, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Ishmeet KumarAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0009-0002-4291-4292
Jayesh VyasAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0000-0002-7407-1974
Asad KhanAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0000-0002-5329-1740
Gargi RamolaAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0009-0007-6714-0162
I IlayarajaAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0009-0004-4719-6757
Lal MuansangiAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.
Anil ChitraAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0000-0002-2052-9548
Pritam PalAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0009-0000-7778-7815
Ritik Kumar SinghAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.ORCID http://orcid.org/0009-0009-0182-6190
M L KambojAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.
T V RajaAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.
Anupama MukherjeeAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India. writetoanupama@gmail.com.ORCID http://orcid.org/0000-0002-4234-4835
Sabyasachi MukherjeeAnimal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India. sabayasachimukherje@gmail.com.ORCID http://orcid.org/0000-0002-1711-6582

Funding

Indian Council of Agricultural Research Project ID: IRC-A91 dated 23.04.2024
6 · The paper itself

Abstract

The Karan Fries (KF), a newly developed dairy cattle (Holstein Friesian × Tharparkar), after nine generations of inter se mating (mating among crossbreds) by maintaining a stable, composite breed structure, is expected to preserve some heterosis or hybrid vigour through the retention of heterozygosity and selective pressure for performance traits. Although a decline in productivity is generally seen from F1 to later inter se generations, the rate of loss of heterosis slows down, allowing the population to reach a new equilibrium. This seems to be an interesting proposition. Therefore, to assess the retained heterosis and to evaluate the current status of the KF population, the present study was conducted, which included a sizeable phenotyped and genotyped animals (n = 355). The analysis identified a stabilized genomic architecture with a mean exotic inheritance of 64.34 ± 0.74% (predominantly Holstein Friesian) and an indigenous contribution of 35.66 ± 0.95% (primarily Tharparkar). Genomic indicators of heterosis revealed a mean Genomic Retained Heterosis (RH

Indexed as

Hybrid VigorLactationAnimalsBreedingCattleFemaleGenome-Wide Association StudyGenotypeIndiaMilkPhenotypeTropical ClimateAdditive and non-additive genetic effectsAdmixture analysisGenomic breed compositionGenomic heterosisJoint-model GWASKaran Fries cattleTropical dairy resilience

Identifiers

PMID42474782

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.