Evidence map›Paper›PMID 42474775›Full record

ArticleSurgery today2026

Secondary breast surgery after initial partial mastectomy for breast cancer in Japan.

Munetsugu Hirata, Yuko Kijima, Sam E Wing, Peng-Lin Lin, Hisamitsu Zaha

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Munetsugu HirataBreast Surgery Department, Fujita Health University Hospital, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, Japan.
Yuko KijimaBreast Surgery Department, Fujita Health University Hospital, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, Japan.
Sam E WingIntuitive Surgical, 1020 Kifer Road, Sunnyvale, CA, USA. sam.wing@intusurg.com.
Peng-Lin LinIntuitive Surgical, 1020 Kifer Road, Sunnyvale, CA, USA.
Hisamitsu ZahaNakagami Hospital, 610 Noborikawa, Okinawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPartial mastectomy for breast cancer may be followed by unplanned secondary surgery due to adverse outcomes, such as the detection of positive margins or cancer recurrence, thus adding burden to patients, providers, and payers. We analyzed the prevalence of this outcome and its economic impact in Japan.

methodsWe utilized the Medical Data Vision (MDV) Research Database to identify a cohort of women in Japan who underwent an index partial mastectomy between 2008 and 2023, following their healthcare encounters up to 5 years postoperatively, including any secondary partial or total mastectomies.

resultsOverall, 49,659 patients with breast cancer underwent primary partial mastectomy, and 2,203 (4.4%) underwent a second surgery. Among these secondary procedures, approximately two-thirds were total mastectomies. The median five-year postoperative healthcare expenditure among patients with one primary partial mastectomy was ¥1.8 million, and ¥2.5 million among patients requiring more than one procedure. Secondary procedures were more common among younger patients, those with larger tumors, and those who did not receive neoadjuvant therapy.

conclusionPartial mastectomy is an essential surgical treatment for early stage breast cancer in Japan. While secondary surgery rates are low compared with other countries, these procedures still have negative financial consequences and extend patients' journeys to remission.

Indexed as

Breast NeoplasmsHealthcare CostsMastectomy, SegmentalReoperation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.