Evidence map›Paper›PMID 42474769›Full record

ArticleSurgery today2026

Survival after pulmonary metastasectomy for pancreatobiliary carcinomas: insights from a nationwide multicenter database.

Taisuke Kaiho, Takahide Toyoda, Hidemi Suzuki, Yoshikane Yamauchi, Noriaki Sakakura, Mingyon Mun, Hiroshi Hashimoto, Takekazu Iwata, Yasushi Shintani, Masayuki Chida and 10 more

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Taisuke KaihoDepartment of General Thoracic Surgery, Chiba University Graduate School of Medicine, 1-8-1, Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Takahide ToyodaDepartment of General Thoracic Surgery, Chiba University Graduate School of Medicine, 1-8-1, Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Hidemi SuzukiDepartment of General Thoracic Surgery, Chiba University Graduate School of Medicine, 1-8-1, Inohana, Chuo-ku, Chiba, 260-8670, Japan. hidemisuzukidesu@yahoo.co.jp.ORCID http://orcid.org/0000-0002-8983-433X
Yoshikane YamauchiDepartment of Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Noriaki SakakuraDepartment of Thoracic Surgery, Aichi Cancer Center, Aichi, Japan.
Mingyon MunDepartment of Thoracic Surgical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Hiroshi HashimotoDepartment of Thoracic Surgery, National Defense Medical College, Saitama, Japan.
Takekazu IwataDivision of Thoracic Surgery, Chiba Cancer Center, Chiba, Japan.
Yasushi ShintaniDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Masayuki ChidaDepartment of General Thoracic Surgery, Dokkyo Medical University, Tochigi, Japan.
Haruhisa MatsugumaDivision of Thoracic Surgery, Tochigi Cancer Center, Tochigi, Japan.
Keisuke AsakuraDivision of Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
Makoto EndoDepartment of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Tomohiko IidaDepartment of Thoracic Surgery, Kimitsu Chuo Hospital, Chiba, Japan.
Mitsutomo KohnoDepartment of General Thoracic Surgery, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Haruhiko KondoDivision of Thoracic and Thyroid Surgery, Kyorin University, Tokyo, Japan.
Norihiko IkedaDivision of Thoracic and Thyroid Surgery, Tokyo Medical University, Tokyo, Japan.
Masaaki SatoDepartment of Thoracic Surgery, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Yukinori SakaoDepartment of Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Metastatic Lung Tumor Study Group of Japan (METAL-J)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePancreatic carcinoma (PC) and biliary tract carcinoma (BTC) may metastasize to the lungs, and surgical resection of these metastases should be considered in selected patients with controlled primary disease. This study evaluated the survival outcomes and prognostic factors in patients who underwent pulmonary metastasectomy for pancreatobiliary carcinoma.

methodsSeventy-eight patients who underwent lung metastasectomy between 1993 and 2019 were included in the Metastatic Lung Tumor Study Group of the Japan database. The clinicopathological characteristics including overall survival (OS), pulmonary metastasis-free survival (PmFS), and disease-free interval (DFI) from primary surgery to lung metastasectomy were analyzed.

resultsWe included 41 men and 37 women with a mean age of 67 years. The primary cancers included 56 PC and 22 BTC cases. Partial resection was performed in 52 patients, segmentectomy in 16, and lobectomy in 10. Five-year OS was 38.3% (43.2% for PC and 28.1% for BTC). Five-year PmFS was 28.3% (28.4% for PC and 27.7% for BTC). The median DFI was 36.0 months (21.0-47.5 months, interquartile range). Larger metastases (> 2 cm) were significantly associated with a poorer survival (hazard ratio, 2.03; 95% confidence interval, 1.06-3.90, p = 0.03).

conclusionLung metastasectomy may be a viable treatment option for select patients with pancreatobiliary carcinoma, particularly those with smaller metastases.

Indexed as

Biliary tract carcinomasPancreatic carcinomasPancreatobiliary carcinomasPulmonary metastasisSurgery

Identifiers

PMID42474769

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